Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
0.350 Biomarker group CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
0.350 Biomarker group BEFREE Equally important, our data suggests that increases in the expression of SOX2 during brain tumor progression are likely to be linked closely with changes in other critical genes that work in concert with SOX2 to enhance the tumorigenicity of brain tumors. 22937156 2012
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
0.350 AlteredExpression group BEFREE Furthermore, miR-21 and SOX2 showed up-regulation and overlapping expression pattern in RCAS/tv-a generated mouse brain tumor specimens. 22931209 2012
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
0.350 AlteredExpression group BEFREE Using a previously described culturing condition that selectively promotes the growth of brain tumor initiating cells, which express the stem cell markers nestin and SOX-2, we characterize the expression of α-amino-3-hydroxy-5-methyl-4-isozolepropionic acid (AMPA)-type glutamate receptor subunits in brain tumor initiating cells derived from glioblastomas. 23110111 2012
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
0.350 Biomarker group BEFREE To further explore the role of Sox2, we performed in vitro analysis with brain tumor stem cells (BTSCs) and established glioma cell lines. 22069467 2011
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
0.350 Biomarker group BEFREE Understanding the functional differences of Sox2 between glioma-initiating cells and normal neural stem cells would contribute to therapeutic approach for treatment of brain tumors. 20537983 2010