Gene: CHEK2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Association of Breast and Ovarian Cancers With Predisposition Genes Identified by Large-Scale Sequencing. 30128536 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Pancreatic cancer as a sentinel for hereditary cancer predisposition. 29945567 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families. 28608266 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer. 29922827 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Novel genetic mutations detected by multigene panel are associated with hereditary colorectal cancer predisposition. 30256826 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Contribution of germline mutations in cancer predisposition genes to tumor etiology in young women diagnosed with invasive breast cancer. 28503720 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Revisiting breast cancer patients who previously tested negative for BRCA mutations using a 12-gene panel. 27798748 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility. 28386063 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Expanding the genotype-phenotype spectrum in hereditary colorectal cancer by gene panel testing. 27696107 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study. 28125075 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. 27153395 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Breast cancer risk is similar for CHEK2 founder and non-founder mutation carriers. 27751358 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA. 26556299 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients. 26822949 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Breast cancer risk is similar for CHEK2 founder and non-founder mutation carriers. 27751358 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS. 27595995 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Novel Nonsense Variants c.58C>T (p.Q20X) and c.256G>T (p.E85X) in the CHEK2 Gene Identified in Breast Cancer Patients from Balochistan. 27510020 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Comparative genomic analysis of primary tumors and metastases in breast cancer. 27028851 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR Implementation of next-generation sequencing for molecular diagnosis of hereditary breast and ovarian cancer highlights its genetic heterogeneity. 27553368 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer. 26976419 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Prevalence of the CHEK2 R95* germline mutation. 27708748 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 CausalMutation disease CLINVAR Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. 27433846 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 GeneticVariation disease CLINVAR A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer. 27067391 2016