Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.360 SomaticCausalMutation disease ORPHANET
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.360 Biomarker disease BEFREE IGH switch breakpoints in Burkitt lymphoma: exclusive involvement of noncanonical class switch recombination. 16736499 2006
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.360 GeneticVariation disease BEFREE The chromosomal translocation t(8;14) is the hallmark of Burkitt's-lymphoma (BL) and fuses the proto-oncogene c-MYC to the IGH locus. 17541401 2007
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.360 GeneticVariation disease BEFREE B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements are aggressive neoplasms with clinical and pathologic features distinct from Burkitt lymphoma and diffuse large B-cell lymphoma. 20118770 2010
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.360 GeneticVariation disease BEFREE A high Ki-67 proliferation index and positive bcl-2 staining (on cytospin slides or cell block material) of cases not conforming to typical Burkitt lymphoma morphology should prompt FISH analysis for c-MYC and/or IGH-BCL2 rearrangements to identify DHL, particularly if tissue biopsy is not expected. 21560252 2011
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.360 GeneticVariation disease BEFREE We have molecularly characterized the recently established Burkitt lymphoma cell line BLUE-1 that carries a t(6;20)(q15;q11.2) rearrangement in addition to the typical t(8;14) with MYC-IGH fusion. 21412927 2011
Entrez Id: 3492
Gene Symbol: IGH
IGH
0.360 GeneticVariation disease BEFREE The chromosomal translocation t(8;14)(q24;q32) with juxtaposition of MYC to enhancer elements in the immunoglobulin heavy chain (IGH) gene locus is the genetic hallmark of the majority of Burkitt lymphoma and a subset of Diffuse large B-cell lymphoma patients. 23673335 2014