Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 AlteredExpression disease BEFREE Burkitt's lymphomas (BLs) are characterized by an activated MYC gene that provides a constitutive proliferative signal. 14712292 2004
Entrez Id: 604
Gene Symbol: BCL6
BCL6
0.100 AlteredExpression disease BEFREE Burkitt lymphoma (BL) is characterized by c-myc translocation and CD10+/bc-2-/bcl-6+ with a very high Ki-67 proliferation index (PI). 17875505 2007
Entrez Id: 27113
Gene Symbol: BBC3
BBC3
0.330 GeneticVariation disease LHGDN Burkitt lymphoma cell lines phenocopy the primary tumors with respect to DNA methylation and diminished PUMA expression, which can be reactivated following inhibition of DNA methyltransferases. 18573879 2008
Entrez Id: 27113
Gene Symbol: BBC3
BBC3
0.330 Biomarker disease CTD_human Burkitt lymphoma cell lines phenocopy the primary tumors with respect to DNA methylation and diminished PUMA expression, which can be reactivated following inhibition of DNA methyltransferases. 18573879 2008
Entrez Id: 27113
Gene Symbol: BBC3
BBC3
0.330 PosttranslationalModification disease BEFREE Burkitt lymphoma cell lines phenocopy the primary tumors with respect to DNA methylation and diminished PUMA expression, which can be reactivated following inhibition of DNA methyltransferases. 18573879 2008
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 Biomarker disease BEFREE Burkitt Lymphoma (BL) is listed in the World Health Organization (WHO) classification of lymphoid tumours as an "aggressive B-cell non-Hodgkin's lymphoma", characterized by a high degree of proliferation of the malignant cells and deregulation of the c-MYC gene. 19670467 2009
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 Biomarker disease BEFREE Burkitt Lymphoma (BL) is listed in the World Health Organization (WHO) classification of lymphoid tumours as an 'aggressive B-cell non-Hodgkin's lymphoma', characterized by a high degree of proliferation of the malignant cells and deregulation of the c-MYC gene. 19844983 2010
Entrez Id: 5079
Gene Symbol: PAX5
PAX5
0.350 Biomarker disease BEFREE Burkitt lymphoma cases were positive for PAX5 (30/30 [100%]), BOB.1 (27/30 [90%]), PU.1 (23/30 [77%]), CD79a (29/30 [97%]), CD22 (14/30 [47%]), CD20 (30/30 [100%]), OCT-2 (23/30 [77%]), and MUM1 (5/30 [17%]). 20023257 2010
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 GeneticVariation disease BEFREE Burkitt's lymphoma (BL) is characterized by translocation of the MYC gene to an immunoglobulin locus. 20160479 2010
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 Biomarker disease BEFREE Burkitt lymphoma accounts for approximately 50% of pediatric cancers in equatorial Africa and a majority of NHL in Uganda. 21127431 2011
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 GeneticVariation disease BEFREE Burkitt lymphoma and a subset of diffuse large B-cell lymphomas are characterized by chromosomal alterations affecting the MYC oncogene on 8q24. 22120970 2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 Biomarker disease BEFREE Burkitt lymphoma is a germinal center B-cell-derived cancer that was instrumental in the identification of MYC as an important human oncogene more than three decades ago. 24492847 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.020 AlteredExpression disease BEFREE BL cancers can be considered a sub-group of Triple negative (TN) cancers since they lack estrogen (ER), progesterone (PR) and Her2 expression. 24693876 2014
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 GeneticVariation disease BEFREE Burkitt lymphoma (BL) is an aggressive B-cell non-Hodgkin lymphoma that is almost uniformly associated with translocations involving the gene for MYC on chromosome 8. 25258344 2014
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 GeneticVariation disease BEFREE Burkitt lymphoma (BL) is an aggressive B cell lymphoma characterized by the reciprocal translocation of the c-Myc gene with immunoglobulin genes. 27044389 2016
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
0.100 Biomarker disease BEFREE Burkitt lymphoma (BL) is an aggressive B-cell neoplasm that is currently treated by intensive chemotherapy in combination with anti-CD20 antibodies. 28064214 2017
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker disease BEFREE Burkitt lymphoma (BL) is an aggressive B-cell neoplasm that is currently treated by intensive chemotherapy in combination with anti-CD20 antibodies. 28064214 2017
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 Biomarker disease BEFREE Burkitt lymphoma (BL) is an aggressive B-cell lymphoma characterized by MYC dysregulation. 28619753 2017
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.020 Biomarker disease BEFREE Burkitt lymphoma (66%) was commonest histopathological subtype; bone marrow was involved in 15% and CSF in 8% cases. 29388861 2018
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
0.010 Biomarker disease BEFREE Burkitt lymphoma (66%) was commonest histopathological subtype; bone marrow was involved in 15% and CSF in 8% cases. 29388861 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
1.000 GeneticVariation disease BEFREE Burkitt lymphoma (BL) is a highly aggressive B-cell lymphoma associated with MYC translocation. 30104685 2018
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
0.100 GeneticVariation disease BEFREE Burkitt lymphoma in Iraqi children: A distinctive form of sporadic disease with high incidence of EBV<sup>+</sup> cases and more frequent expression of MUM1/IRF4 protein in cases with head and neck presentation. 30207048 2018
Entrez Id: 84939
Gene Symbol: PWWP3A
PWWP3A
0.080 GeneticVariation disease BEFREE Burkitt lymphoma in Iraqi children: A distinctive form of sporadic disease with high incidence of EBV<sup>+</sup> cases and more frequent expression of MUM1/IRF4 protein in cases with head and neck presentation. 30207048 2018
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.070 Biomarker disease BEFREE Burkitt's lymphoma (BL) is an aggressive lymphoma sub-type with high 18F-FDG avidity, but no well established evidence of PET/CT's role in treatment evaluation or prognosis is currently available. 30788775 2019
Entrez Id: 958
Gene Symbol: CD40
CD40
0.100 Biomarker disease BEFREE Burkitt's lymphoma and Epstein-Barr virus-transformed B cell lines and tonsilar B lymphocytes were treated with the anti-CD40 mAb for various lengths of time. 7515102 1994