| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | AlteredExpression | group | BEFREE | Head and neck carcinomas show frequent activation of c-MYC function and SIRT6 down-regulation, which contributes to a strong dependence on glucose and glutamine availability. | 29790697 | 2018 | ||||
|
0.400 | AlteredExpression | group | BEFREE | p53 mutations and myc gene amplification and expression were studied in 119 lung carcinomas of all histological types. | 8014012 | 1994 | ||||
|
0.400 | AlteredExpression | group | BEFREE | Consecutive tissue sections were investigated for expression of the major histocompatibility complex class I (MHC-I) and c-myc using immunohistochemical double staining procedures, since a role has been suggested for the c-myc protein in MHC-I down-regulation and c-myc overexpression has been described in cervical carcinomas. | 8414499 | 1993 | ||||
|
0.400 | AlteredExpression | group | BEFREE | Gene alteration of the c-myc locus, as well as overexpression of the c-myc oncogene, appeared to be limited, and analysis of the c-myc gene yielded limited prognostic value in human esophageal carcinomas. | 1444241 | 1992 | ||||
|
0.400 | AlteredExpression | group | BEFREE | Only 4% of basal-like carcinomas showed MYC amplification, compared to 8.75% and 10.7% of luminal and HER2 tumours respectively. | 17158641 | 2007 | ||||
|
0.400 | AlteredExpression | group | BEFREE | On the other hand, the expression of MYC and p53 was more frequent in gallbladder carcinomas than in control samples (p = 0.002, p = 0.046, respectively). | 25200035 | 2015 | ||||
|
0.400 | AlteredExpression | group | BEFREE | In both models we show that c-MYC and SIRT1 protein expression increased through progression from hyperplasia to invasive carcinomas and metastases. | 31442917 | 2019 | ||||
|
0.400 | AlteredExpression | group | BEFREE | For some carcinomas there was a good correlation between c-myc protein and mRNA levels. | 2569035 | 1989 |