Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE Data on the distribution of GATA3 expression in gynecologic malignancies is somewhat limited, particularly across different histologic subtypes of ovarian, endometrial, and cervical carcinomas. 30059453 2019
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE We aimed to assess the prognostic utility of immunohistochemistry (IHC) for basal markers: cytokeratin 5/6 (CK5/6) and 14 (CK14), and luminal markers: cytokeratin 20 (CK20) and Gata3 in muscle invasive urothelial carcinomas (MIBC). 31494492 2019
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE This finding expands the pattern of transcription factors that are used to classify adenohypophysial tumors and is important in the differential diagnosis of sellar tumors, as GATA3 expression is also a feature of primary sellar paragangliomas as well as carcinomas that may metastasize to the sella. 30390035 2019
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE The expression of GATA-3, mammaglobin, GCDFP-15 and NY-BR-1 is lower in TNBC-s than in breast carcinomas in general, and this may be even lower in basal-like carcinomas. 28470571 2018
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE Herein, we compared the performance of GATA3 and TTF1 to the traditional markers used for mesonephric carcinomas, CD10 and calretinin. 30148742 2018
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE Carcinomas without overt cytoplasmic mucin (endometrioid, usual-type endocervical, clear cell, and mesonephric carcinomas) can be subclassified using HR-HPV ISH, ER, and GATA3, whereas carcinomas with easily appreciated cytoplasmic mucin (endometrioid carcinoma with mucinous features, HPVA mucinous, and gastric-type carcinomas) can be subclassified with HR-HPV ISH and ER. 29851704 2018
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE GATA binding protein 3 (GATA3) immunohistochemical expression is commonly considered to be a sensitive and specific diagnostic marker for breast and urothelial carcinomas in surgical pathology practice. 30293951 2018
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE GATA-binding protein 3 (GATA3) is a tumor suppressor that shows increased expression in several types of human malignancies including breast and bladder carcinomas. 29434343 2018
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE GATA-3 was expressed in 1.0% of lung carcinomas, with sensitivity and specificity of 82.5 and 99.0% in differentiating IBC and lung carcinoma. 29340880 2018
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE GATA-binding protein 3 (GATA3) is a sensitive and relatively specific marker in breast and urothelial carcinomas. 28428285 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE All 19 sarcomatoid/desmoplastic malignant mesotheliomas examined showed strong diffuse staining for GATA3 (no case scored <3, mean score±SD for all 19 cases 5.4±0.9), whereas only 2 of 13 sarcomatoid carcinomas of the lung stained positively for GATA3 and the staining was weak and patchy (score 2 for each case, mean±SD for all 13 cases 0.4±0.8). 28614203 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE None of the medullary and metaplastic carcinomas expressed GATA3. 28215639 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE GATA-binding protein 3 (GATA3) is a well-studied transcription factor found to be essential in the development of luminal breast epithelium and has been identified in a variety of tumour types, including breast and urothelial carcinomas, making it a useful immunohistochemistry marker in the diagnosis of both primary and metastatic disease. 28211079 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE However, occasional GATA3 expression in the most common source of metastases within the adrenal gland, metastatic pulmonary adenocarcinoma, may confound the diagnosis due to the overlapping expression with pheochromocytoma and other carcinomas. 28374498 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE GATA3 expression is positively correlated with ER-positive, PR-positive, and HER2-positive carcinomas. 28038704 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 GeneticVariation group BEFREE However, an increase in GATA3 mutations and fewer copy number changes were noted in DCIS compared with invasive carcinomas. 28338653 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 GeneticVariation group BEFREE That fact will affect the interpretation of GATA3 stains in the context of possible metastasis from primary bladder carcinomas with variant morphologic patterns, as well as their distinction from secondary bladder involvement by tumors of nonurothelial origin. 26317312 2016
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE Samples from salivary gland carcinomas (n = 43) were analysed by immunohistochemistry (caspase 14, filaggrin, GATA3 and Ki67) and fluorescence in situ hybridization. 25257949 2015
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 AlteredExpression group BEFREE Interestingly, GATA3 levels were significantly lower in carcinomas with lung relapse compared to those with metastatic recurrence to other organs, thus reflecting the findings in animal models. 26486740 2015
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE GATA-binding protein 3 (GATA-3) has emerged recently as a sensitive and relatively specific immunomarker for breast and urothelial carcinomas, but the data documenting its expression in ER-negative breast carcinomas are limited; this often poses a dilemma in the setting of metastases. 24713735 2014
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE A commercially available monoclonal antibody against GATA3 stained 67% of 308 urothelial carcinomas, but none of the prostate or renal carcinomas. 17460449 2007
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group BEFREE To validate its prognostic utility, we did a tissue microarray analysis on a cohort of 139 consecutive invasive carcinomas (n = 417 tissue samples) immunostained with a monoclonal antibody against GATA3. 16357129 2005
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
0.400 Biomarker group CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942 2005