DisGeNET - a database of gene-disease associations

Adenocarcinoma of prostate, C0007112

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	367
Gene Symbol:	AR

0.600

CausalMutation

disease

CGI

Entrez Id:	367
Gene Symbol:	AR

0.600

GenomicAlterations

disease

CGI

Entrez Id:	5728
Gene Symbol:	PTEN

PTEN

0.480

GenomicAlterations

disease

CGI

Entrez Id:	5728
Gene Symbol:	PTEN

PTEN

0.480

CausalMutation

disease

CGI

Entrez Id:	673
Gene Symbol:	BRAF

BRAF

0.430

CausalMutation

disease

CGI

Entrez Id:	8405
Gene Symbol:	SPOP

SPOP

0.420

CausalMutation

disease

CGI

Entrez Id:	207
Gene Symbol:	AKT1

AKT1

0.340

CausalMutation

disease

CGI

Entrez Id:	1956
Gene Symbol:	EGFR

EGFR

0.320

CausalMutation

disease

CGI

Entrez Id:	4609
Gene Symbol:	MYC

MYC

0.320

GenomicAlterations

disease

CGI

Entrez Id:	1316
Gene Symbol:	KLF6

KLF6

0.310

CausalMutation

disease

CGI

Entrez Id:	8312
Gene Symbol:	AXIN1

AXIN1

0.300

CausalMutation

disease

CGI

Entrez Id:	11200
Gene Symbol:	CHEK2

CHEK2

0.300

CausalMutation

disease

CGI

Entrez Id:	672
Gene Symbol:	BRCA1

BRCA1

0.300

CausalMutation

disease

CGI

Entrez Id:	8379
Gene Symbol:	MAD1L1

MAD1L1

0.300

CausalMutation

disease

CGI

Entrez Id:	6790
Gene Symbol:	AURKA

AURKA

0.300

GenomicAlterations

disease

CGI

Entrez Id:	675
Gene Symbol:	BRCA2

BRCA2

0.300

CausalMutation

disease

CGI

Entrez Id:	11200
Gene Symbol:	CHEK2

CHEK2

0.300

GenomicAlterations

disease

CGI

Entrez Id:	79728
Gene Symbol:	PALB2

PALB2

0.300

CausalMutation

disease

CGI

Entrez Id:	3169
Gene Symbol:	FOXA1

FOXA1

0.300

CausalMutation

disease

CGI

Entrez Id:	2175
Gene Symbol:	FANCA

FANCA

0.300

CausalMutation

disease

CGI

Entrez Id:	8312
Gene Symbol:	AXIN1

AXIN1

0.300

GenomicAlterations

disease

CGI

Entrez Id:	2048
Gene Symbol:	EPHB2

EPHB2

0.300

CausalMutation

disease

CGI

Entrez Id:	472
Gene Symbol:	ATM

ATM

0.300

CausalMutation

disease

CGI

Entrez Id:	3066
Gene Symbol:	HDAC2

HDAC2

0.300

CausalMutation

disease

CGI

Entrez Id:	613
Gene Symbol:	BCR

BCR

0.010

AlteredExpression

disease

BEFREE

<b>Results</b>: High levels of WISP1 correlated with BCR-free survival in prostate adenocarcinoma and overall survival in primary melanoma, low-grade glioma, and kidney papillary cell carcinoma.

31069142

2019