Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		0.010 Biomarker disease LHGDN Mast cells in basal cell carcinoma express VEGF, IL-8 and RANTES. 12660426 2003
Entrez Id: 3621
Gene Symbol: ING1
ING1 		0.010 AlteredExpression disease LHGDN Analyses of the tumour suppressor ING1 expression and gene mutation in human basal cell carcinoma. 12632089 2003
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.010 GeneticVariation disease LHGDN Basal cell carcinoma is associated with high TNF-alpha release but nor with TNF-alpha polymorphism at position--308. 14714556 2003
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		0.010 Biomarker disease LHGDN Mast cells in basal cell carcinoma express VEGF, IL-8 and RANTES. 12660426 2003
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN Spectrum of PTCH mutations in Italian nevoid basal cell-carcinoma syndrome patients: identification of thirteen novel alleles. 15459969 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.130 AlteredExpression disease LHGDN Phosphorylation state of tumor-suppressor gene p53 product overexpressed in skin tumors. 15492790 2004
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R 		0.010 AlteredExpression disease LHGDN Expression of insulin-like growth factor-I receptor in primary cutaneous carcinomas. 15059221 2004
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 Biomarker disease LHGDN Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays. 16203740 2005
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC. 15592520 2005
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN DHPLC analysis of patients with Nevoid Basal Cell Carcinoma Syndrome reveals novel PTCH missense mutations in the sterol-sensing domain. 16088933 2005
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		0.310 GeneticVariation disease LHGDN Polymorphism in the nuclear excision repair gene ERCC2/XPD: association between an exon 6-exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma. 15776433 2005
Entrez Id: 4694
Gene Symbol: NDUFA1
NDUFA1 		0.010 AlteredExpression disease LHGDN Downregulation of NDUFA1 and other oxidative phosphorylation-related genes is a consistent feature of basal cell carcinoma. 15854127 2005
Entrez Id: 5325
Gene Symbol: PLAGL1
PLAGL1 		0.010 AlteredExpression disease LHGDN The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas. 16179495 2005
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.010 AlteredExpression disease LHGDN Pigmentation in basal cell carcinoma involves enhanced endothelin-1 expression. 15946241 2005
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN PTCH mutations: distribution and analyses. 16419085 2006
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN Germline mutations of the PTCH gene in families with odontogenic keratocysts and nevoid basal cell carcinoma syndrome. 16675912 2006
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN MC1R and PTCH gene polymorphism in French patients with basal cell carcinomas. 16645598 2006
Entrez Id: 7507
Gene Symbol: XPA
XPA 		0.320 GeneticVariation disease LHGDN XPA, haplotypes, and risk of basal and squamous cell carcinoma. 16513681 2006
Entrez Id: 4157
Gene Symbol: MC1R
MC1R 		0.120 GeneticVariation disease LHGDN MC1R and PTCH gene polymorphism in French patients with basal cell carcinomas. 16645598 2006
Entrez Id: 2735
Gene Symbol: GLI1
GLI1 		0.030 AlteredExpression disease LHGDN Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes. 16434164 2006
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3 		0.010 Biomarker disease LHGDN RUNX3 protein is overexpressed in human basal cell carcinomas. 16767156 2006
Entrez Id: 26585
Gene Symbol: GREM1
GREM1 		0.010 AlteredExpression disease LHGDN Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. 17003113 2006
Entrez Id: 652
Gene Symbol: BMP4
BMP4 		0.010 AlteredExpression disease LHGDN Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. 17003113 2006
Entrez Id: 4613
Gene Symbol: MYCN
MYCN 		0.010 AlteredExpression disease LHGDN Recurrent NMYC copy number gain and high protein expression in basal cell carcinoma. 16596176 2006
Entrez Id: 650
Gene Symbol: BMP2
BMP2 		0.010 AlteredExpression disease LHGDN Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. 17003113 2006