Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6391
Gene Symbol: SDHC
SDHC
0.140 GeneticVariation disease BEFREE Most SDH-deficient tumors show SDHB mutation, with only a small number of RCC with SDHC or SDHD having been reported to date. 26476567 2015
Entrez Id: 6391
Gene Symbol: SDHC
SDHC
0.140 GeneticVariation disease BEFREE Germline mutations in Von Hippel-Lindau (VHL), succinate dehydrogenase subunit B (SDHB), SDHC, and SDHD have been detected in individuals with synchronous or metachronous pheochromocytoma/paraganglioma (PHEO/PGL) and renal cell carcinoma (RCC). 25800244 2015
Entrez Id: 6391
Gene Symbol: SDHC
SDHC
0.140 GeneticVariation disease BEFREE Blood DNA, paragangliomas, and RCCs were analyzed for mutations and loss-of-heterozygosity (LOH) in/flanking SDHC and VHL. 22351710 2012
Entrez Id: 6391
Gene Symbol: SDHC
SDHC
0.140 GeneticVariation disease BEFREE We investigated whether germline mutations in fumarate hydratase (FH) or succinate dehydrogenase subunit genes (SDHB, SDHC, SDHD) were associated with RCC susceptibility in 68 patients with no clinical evidence of an RCC susceptibility syndrome. 18728283 2008
Entrez Id: 6391
Gene Symbol: SDHC
SDHC
0.140 Biomarker disease HPO