Gene: VEGFA ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease BEFREE Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck. 10213212 1999
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE VEGF-A expression correlates with SCCRO expression in these primary human lung squamous cell carcinomas and is a predictor of clinical behavior. 15123463 2004
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease BEFREE VEGF is also a promoter of angiogenesis in many tumour types, and has therefore been subject to numerous studies in oral dysplasia and squamous cell carcinomas. 16144770 2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE Vascular endothelial growth factor (VEGF) protein expression was significantly increased in squamous cell carcinoma (SCC) samples from EP2 TG mice compared that of WT mice. 16607275 2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 GeneticVariation disease LHGDN Vascular endothelial growth factor 936 C/T polymorphism is associated with vascular invasion in oral squamous cell carcinoma. 18299215 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE VEGF-A expression showed a correlation to histological type with increased expression in adenocarcinomas as compared to squamous cell carcinomas. 19324448 2009
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE VEGF and VEGFRs expression in oral squamous cell carcinoma. 19942948 2009
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease BEFREE VEGF expression was positively associated with the MVD count of hypopharyngeal squamous cell carcinomas (r = 0.582, P = 0.000); however, integrin β1 was not associated with VEGF or MVD (P > 0.05). 25158264 2014
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease BEFREE VEGF PI values were higher in pT1, pT2 then in pT3 and in the pN0 SCC, but without statistically significant differences. 28523303 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE VEGF was expressed in 50% of the squamous cell carcinomas (SCC) and carcinoids but none of the others. p53 mutations occurred in 14 tumours (52%), and K-ras mutations were found in two adenocarcinomas and one SCC; there was no correlation between the mutations and VEGF expression. 9683299 1998
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE A high expression of VEGF (> or = 25% of cells) was observed in 75% and 73.34% of squamous cell carcinomas and adenocarcinomas, respectively, and in all cases of large cell carcinomas. 14981918 2004
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE Adenocarcinomas showed significantly higher VEGF mRNA expression and a higher protein staining score than squamous-cell carcinomas. 11102890 2000
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease BEFREE Adenocarcinomas showed significantly higher staining scores of both VEGF and αSMA than squamous cell carcinomas did. 29970531 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 GeneticVariation disease BEFREE Association of VEGF-A genetic polymorphisms with cancer risk and survival in advanced-stage oral squamous cell carcinoma patients. 22818823 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 GeneticVariation disease BEFREE Associations between single-nucleotide polymorphisms of the VEGF gene and long-term prognosis of oral squamous cell carcinoma. 23227881 2013
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE Combined Analysis of Vascular Endothelial Growth Factor Expression with Cyclooxygenase-2 and Mast Cell Density in Oral Squamous Cell Carcinoma. 27577989 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE Comparison of immunohistochemical expression of vascular endothelial growth factor and CD105 in oral squamous cell carcinoma: Its correlation with prognosis. 29516931 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease LHGDN Correlation of cyclooxygenase-2 pathway and VEGF expression in head and neck squamous cell carcinoma. 12883661 2004
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease LHGDN Cyclooxygenase-2 expression after preoperative chemoradiotherapy correlates with more frequent esophageal cancer recurrence. 17511025 2007
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE Elevated VEGFA mRNA levels in oral squamous cell carcinomas and tumor margins: a preliminary study. 26861159 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE Expression of vascular endothelial growth factor in human oral squamous cell carcinoma: its association with tumour progression and p53 gene status. 10023341 1998
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 AlteredExpression disease BEFREE Expression of vascular endothelial growth factor (VEGF) in patients with oral squamous cell carcinoma and its clinical significance. 24833243 2014
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease BEFREE Expression of BDNF, TrkB, VEGF and CD105 is associated with pelvic lymph node metastasis and prognosis in IB2-stage squamous cell carcinoma. 31777532 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease LHGDN Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck. 15254682 2004
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 GeneticVariation disease BEFREE For the VEGF -2578C/A polymorphism, the combined results showed that there exist highly significant risk factors for individuals carrying the A allele resulting in lung cancer, and the magnitude of this effect was similar in smoker patients and squamous cell carcinoma (SCC) patients. 23982876 2014