|
SERPINB3
|
0.400 |
Biomarker
|
disease |
BEFREE |
Squamous cell carcinoma antigens 1 and 2 (SCCA1 and 2, SERPIN B3 and B4), members of the ovalbumin serpin (ov-serpin)/clade B serpin family, were originally discovered as tumor-specific antigens and are used as tumor markers for various kinds of squamous cell carcinomas.
|
29642409 |
2018 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
BEFREE |
This suggests that combined measurements of both serum SCCA1 and SCCA2 concentrations can be very useful for distinguishing sinonasal inverted papilloma from SCC.
|
30376194 |
2018 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
BEFREE |
The SCCA1 promoter was analyzed by dual luciferase assay and substituted with the E1A promoter to construct the oncolytic adenovirus to determine the squamous cell carcinoma-specific cell lysis.
|
20527047 |
2010 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
LHGDN |
Evaluation of serum squamous cell carcinoma antigen as a novel biomarker for diagnosis of hepatocellular carcinoma in Egyptian patients.
|
19112206 |
2009 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Humoral autoimmune responses to the squamous cell carcinoma antigen protein family in psoriasis.
|
18385761 |
2008 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
High SerpinB3 expression levels, invariably associated with chemoresistance, had contrasting prognostic impact in untreated squamous cell carcinomas (hazard ratio [HR], 0.43; 95% CI, 0.18 to 0.93) or adenocarcinomas (HR, 2.09; 95% CI, 1.03 to 4.72).
|
16549823 |
2006 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Squamous cell carcinoma-antigen messenger RNA level in peripheral blood predicts recurrence after resection in patients with esophageal squamous cell carcinoma.
|
16701102 |
2006 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Molecular detection of squamous cell carcinoma antigen transcripts in peripheral blood of cancer patients.
|
16681421 |
2006 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
BEFREE |
We recently found that the squamous cell carcinoma antigens 1 (SCCA1) and SCCA2 are novel biomarkers of bronchial asthma, downstream of IL-4 and IL-13.
|
16238792 |
2005 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
BEFREE |
This study examined the effect of squamous cell carcinoma antigen 1 (SCCA1) and SCCA2 on TNF-alpha-induced cell death in human oral squamous cell carcinoma cell lines.
|
16006770 |
2005 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Transient increase in squamous cell carcinoma antigen expression in cultured cervical carcinoma CaSki cells in response to exposure to cis-diamminedichloroplatinum.
|
15001834 |
2004 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
CTD_human |
Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis.
|
15274141 |
2004 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Surface expression of squamous cell carcinoma antigen (SCCA) can be increased by the preS1(21-47) sequence of hepatitis B virus.
|
14993646 |
2004 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
LHGDN |
Regulation of squamous cell carcinoma antigen production by E-cadherin mediated cell-cell adhesion in squamous cell carcinoma cell line.
|
14719077 |
2004 |
|
SERPINB3
|
0.400 |
Biomarker
|
disease |
BEFREE |
These findings suggest that the transcriptional regulation of SCCA1 and SCCA2 might differ among squamous cell carcinoma, keratinocyte and adenocarcinoma cells, and that SCCA1 promoter might be a potential target of gene therapy for squamous cell carcinoma.
|
11267667 |
2001 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Reverse transcription (RT)-PCR of the squamous cell carcinoma cell line showed the existence of a 156 base shorter transcript compared with that of SCCA1 cDNA.
|
11406281 |
2001 |
|
SERPINB3
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
These findings suggest that SCCA1 is mainly expressed in squamous cell carcinoma, keratinocyte and non-squamous cell carcinoma cell lines and that the ratio of SCCA1 to SCCA2 expression might be a novel marker for the detection of squamous cell carcinoma.
|
11182054 |
2001 |