Gene: TNNT2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease HPO
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease CLINGEN Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle. 1934353 1991
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy. 7898523 1995
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. 8205619 1994
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease CLINGEN Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. 8205619 1994
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Clinical manifestations of hypertrophic cardiomyopathy with mutations in the cardiac beta-myosin heavy chain gene or cardiac troponin T gene. 8951566 1996
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease BEFREE Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action. 8958207 1996
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action. 8958207 1996
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Sudden death due to troponin T mutations. 9060892 1997
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Expression of a mutant (Arg92Gln) human cardiac troponin T, known to cause hypertrophic cardiomyopathy, impairs adult cardiac myocyte contractility. 9201030 1997
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease CLINGEN A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. 9637714 1998
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. 9637714 1998
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Ca2+ sensitization and potentiation of the maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy. 10085122 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease CLINGEN Identification of a contractile deficit in adult cardiac myocytes expressing hypertrophic cardiomyopathy-associated mutant troponin T proteins. 10330428 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease CLINGEN Functional consequences of a carboxyl terminal missense mutation Arg278Cys in human cardiac troponin T. 10405326 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease CLINGEN Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy. 10449439 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR The origins of hypertrophic cardiomyopathy-causing mutations in two South African subpopulations: a unique profile of both independent and founder events. 10521296 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy. 10525521 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 GeneticVariation disease CLINVAR A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy. 10525521 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants. 10529204 1999
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy. 10617660 2000
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 CausalMutation disease CLINVAR Functional consequences of the deletion mutation deltaGlu160 in human cardiac troponin T. 10731693 2000
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 GeneticVariation disease CLINVAR Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy. 11034944 2000
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.800 Biomarker disease CLINGEN Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation. 11060294 2001