Gene: TRIM63 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 Biomarker disease BEFREE These findings implicate an impaired interaction between titin and MURF1 as a novel mechanism underlying the pathogenesis of HCM. 31628103 2019
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 Biomarker disease CLINGEN New cardiac and skeletal protein aggregate myopathy associated with combined MuRF1 and MuRF3 mutations. 25801283 2015
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 GeneticVariation disease BEFREE The p.Q247X variant in TRIM63 is not likely to be a highly penetrant variant causing hypertrophic cardiomyopathy. 24436435 2014
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 GeneticVariation disease BEFREE These data strongly supported that rare variants in MuRF1 and MuRF2 are associated with higher penetrance and more severe clinical manifestations of HCM. 24865491 2014
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 GeneticVariation disease BEFREE TRIM63 mutations, identified in patients with HCM, impart loss-of-function effects on E3 ligase activity and are probably causal mutations in HCM. 22821932 2012
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 Biomarker disease CLINGEN To determine the pathogenic role of TRIM63 in human hypertrophic cardiomyopathy (HCM). 22821932 2012
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 Biomarker disease CLINGEN Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I. 15601779 2004
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 Biomarker disease CLINGEN Identification of ubiquitin ligases required for skeletal muscle atrophy. 11679633 2001
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63 		0.640 GeneticVariation disease CLINVAR