Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE New and known genetic determinants of plasma levels of LDL cholesterol, lipoprotein(a), and triglyceride-rich lipoproteins are concordant with both the magnitude and direction of the expected risk of cardiovascular disease, whereas this is unclear for HDL cholesterol. 21358543 2011
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE To examine the relations between genetic loci, plasma lipoprotein(a) [Lp(a)] levels, and cardiovascular disease (CVD) risk among diabetic patients and compare with the observations in the general population. 21900290 2012
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Increased levels of lipoprotein (a) [Lp(a)] have been considered an independent risk factor for cardiovascular disease, but the mechanism behind this relationship is not completely understood. 9580386 1998
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE 1.Elevated plasma lipoprotein (a) (Lp(a)) concentrations have been correlated with an increased risk of premature cardiovascular disease. 10225140 1999
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Elevated low-density lipoprotein cholesterol and/or lipoprotein(a) are established risk factors for cardiovascular disease (CVD). 30799420 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Increased plasma level of lipoprotein(a) (Lpa) is a risk factor of cardiovascular diseases. 30071823 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Therefore, in the evaluation of a fully automated, particle-enhanced turbidimetric immunoassay for the measurement of lipoprotein(a) we have determined its reference interval in the Spanish population, an area with the lowest incidence of cardiovascular disease in Europe. 12633762 2003
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group LHGDN ApolipoproteinA1-75 G/A (M1-) polymorphism and lipoprotein(a); anti- vs. pro-Atherogenic properties. 17683612 2007
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: The EPIC-Norfolk prospective population study. 27998826 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lipoprotein (a) [Lp(a)], an inherited lipoprotein, is associated with premature CVD, but its impact on cardiovascular health during childhood is less understood. 29948030 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Those with evidence of CAD were significantly more likely to be male, inactive, diabetic and with a family history of CVD than participants without CAD.About 20% of patients had lipoprotein(a) (Lp(a)) concentrations above 106.9 nmol/L (fifth quintile). 31481563 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE It is well-known that Lp(a) levels have an impact on increased risk of CVD which is affected by LPA gene. 31113255 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lipoprotein(a) [Lp(a)] is an emerging genetic risk factor for cardiovascular disease (CVD). 29960898 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lipoprotein(a) [Lp(a)] has been identified as a risk factor for cardiovascular disease. 28203441 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lipoprotein (a) [Lp(a)] is an established causal risk factor for cardiovascular disease (CVD), independently of low-density lipoproteins (LDL) and other risk factors. 31493849 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular disease; we highlight the most recent research initiatives that have sought to define Lp(a)-dependent pathogenicity as well as pharmacologic approaches to lowering Lp(a). 22327610 2012
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lipoprotein(a) [Lp(a)] has been considered as a causal risk factor for cardiovascular disease (CVD) in the general population and levels vary in different ethnicities. 31683090 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lp(a) [lipoprotein (a)] is composed of apoB (apolipoprotein B) and apo(a) [apolipoprotein (a)] and is an independent risk factor for cardiovascular disease and aortic stenosis. 28729361 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE In this context, a major resurgence in interest in lipoprotein (a) [Lp(a)] has occurred in light of its association with CVD. 28120711 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Lipoprotein(a) (Lp(a)) is a causal risk factor for cardiovascular disorders including coronary heart disease and calcific aortic valve stenosis. 29852400 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Elevated Lipoprotein(a) (Lp[a]) is a well-known risk factor for cardiovascular disease. 31023762 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Progress continues to be made in the understanding of Lp(a) metabolism, and Lp(a) levels, rather than apolipoprotein (a) isoform size, have been shown to be more closely related to CVD risk. 24977982 2014
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Elevated levels of lipoprotein(a) [Lp(a)] are an independent risk factor for cardiovascular disease (CVD), particularly in individuals with type 2 diabetes. 28386638 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Elevated serum lipoprotein(a) [Lp(a)] levels are associated with increased cardiovascular disease risk. 31220285 2019