Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE There was no association between LTL and duration of GH treatment, cumulative GH dose or several risk factors for type 2 diabetes mellitus or cardiovascular disease. 31689713 2019
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 GeneticVariation group BEFREE In conclusion, the pathophysiology of endothelial dysfunction in the condition of GH and IGF-1 excess remains a crucial area of investigation to fully dissect the association of acromegaly with cardiovascular disease complications. 31396153 2019
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE In summary, we postulate that short-term GH administration could be useful to treat cardiovascular diseases. 29346331 2018
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE This process, preferentially termed "developmental programming" as part of the developmental origins of health and disease (DOHaD) framework, leads to phenotypic outcomes in offspring that closely resemble those of individuals with untreated growth hormone (GH) deficiency, including increased adiposity and cardiovascular disorders. 28786951 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE Growth hormone (GH) has been linked to cardiovascular disease but the exact mechanism of this association is still unclear. 28511669 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE Acromegaly is characterized by growth hormone (GH) and insulin-like growth factor 1 (IGF1) excess and is accompanied by an increased cardiovascular diseases (CVD) risk. 28611056 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE There is an ongoing discussion whether high doses of growth hormone (GH) may lead to cardiovascular diseases. 28068655 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE It is well documented that the cardiovascular system is an important target organ for growth hormone (GH) and insulin-like growth factor (IGF)-1 in humans, and GH /IGF-1 deficiency significantly increases the risk for cardiovascular diseases (CVD). 29375617 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE Our objective was to find genetic determinants of fasting GH in order to facilitate future efforts of analyzing the association between fasting growth hormone and cardiovascular disease. 29065852 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Therapeutic group CTD_human Evidence for a decrease in cardiovascular risk factors following recombinant growth hormone administration in abstinent anabolic-androgenic steroid users. 17324600 2007
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group LHGDN Growth hormone secretion is impaired but not related to insulin sensitivity in non-obese patients with polycystic ovary syndrome. 14998943 2004
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group LHGDN In this paper, the effects of GH on the physiological mechanisms of the cardiovascular system are discussed, including the effect of GHD on cardiovascular disease risk. 15591764 2004
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.400 Biomarker group BEFREE Hypothetically, intrauterine programming of the GH/IGF axis may influence postnatal growth, insulin resistance and consequently the risk of cardiovascular disease. 14671411 2003