Tissue typing (HLA-A, -B and -DR) was carried out on 92 patients with coeliac disease (CD) and on a further 71 first degree relatives of 13 of these patients.
28 patients with coeliac disease (C.D.) were typed for the HLA-A, -B, and -D loci by several techniques.It was found that C.D. is primarily associated with the DW3 determinant and only secondarily with HLA-B8.