Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.300 Therapeutic phenotype CTD_human Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA. 2982513 1985
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.300 Biomarker phenotype CTD_human Oncogenic potential of bcl-2 demonstrated by gene transfer. 2848196 1988
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.300 Biomarker phenotype CTD_human Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells. 2543982 1989
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.300 Biomarker phenotype CTD_human Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells. 2543982 1989
Entrez Id: 2353
Gene Symbol: FOS
FOS
0.300 Biomarker phenotype CTD_human Suppression of oncogene-induced transformation by quercetin and retinoic acid in rat liver epithelial cells. 8777434 1995
Entrez Id: 3725
Gene Symbol: JUN
JUN
0.300 Biomarker phenotype CTD_human Suppression of oncogene-induced transformation by quercetin and retinoic acid in rat liver epithelial cells. 8777434 1995
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.300 Therapeutic phenotype CTD_human Manganese superoxide dismutase expression inhibits soft agar growth in JB6 clone41 mouse epidermal cells. 9067545 1997
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.300 Biomarker phenotype CTD_human Manganese superoxide dismutase expression inhibits soft agar growth in JB6 clone41 mouse epidermal cells. 9067545 1997
Entrez Id: 8668
Gene Symbol: EIF3I
EIF3I
0.300 Biomarker phenotype CTD_human Molecular cloning and functional analysis of a novel cadmium-responsive proto-oncogene. 11830523 2002
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.300 Biomarker phenotype CTD_human Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters. 12115494 2002
Entrez Id: 6566
Gene Symbol: SLC16A1
SLC16A1
0.300 Biomarker phenotype CTD_human Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy. 11953883 2002
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.300 Biomarker phenotype CTD_human Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters. 12115494 2002
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
0.300 Biomarker phenotype CTD_human Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy. 11953883 2002
Entrez Id: 1950
Gene Symbol: EGF
EGF
0.300 Biomarker phenotype CTD_human Inhibition of cell transformation by resveratrol and its derivatives: differential effects and mechanisms involved. 12687016 2003
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.010 AlteredExpression phenotype LHGDN Role of Vitamin D receptor gene in radiation-induced neoplastic transformation of human breast epithelial cell. 12957667 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.500 Biomarker phenotype CTD_human A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. 15550242 2004
Entrez Id: 8848
Gene Symbol: TSC22D1
TSC22D1
0.300 Biomarker phenotype CTD_human Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling. 15089088 2004
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 Biomarker phenotype CTD_human Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase. 14700523 2004
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
0.300 Biomarker phenotype CTD_human A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. 15550242 2004
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.300 Biomarker phenotype CTD_human Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase. 14700523 2004
Entrez Id: 5447
Gene Symbol: POR
POR
0.300 Biomarker phenotype CTD_human Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling. 15089088 2004
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
0.300 Biomarker phenotype CTD_human Phosphorylation of galectin-3 contributes to malignant transformation of human epithelial cells via modulation of unique sets of genes. 16322222 2005
Entrez Id: 6319
Gene Symbol: SCD
SCD
0.010 AlteredExpression phenotype LHGDN High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts. 15708362 2005
Entrez Id: 274
Gene Symbol: BIN1
BIN1
0.010 Biomarker phenotype LHGDN Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival. 17218774 2007
Entrez Id: 1950
Gene Symbol: EGF
EGF
0.300 Biomarker phenotype CTD_human Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. 18245498 2008