Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Biomarker disease BEFREE Blood-brain barrier (BBB) breakdown and inflammatory responses are the major causes of tissue-type plasminogen activator (tPA)-induced hemorrhagic transformation (HT), while high-mobility group box 1 (HMGB1) exacerbates inflammatory damage to BBB during the process of brain ischemia/reperfusion. 30139371 2018
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Red blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the newborn pig. 21037505 2011
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Time of day, outcome, and response to thrombolytic therapy: the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trial experience. 20123226 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human [Thrombolysis in acute ischemic stroke in basic hospitals. four cases reports]. 20488584 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Lack of association between hyperglycaemia at arrival and clinical outcomes in acute stroke patients treated with tissue plasminogen activator. 20536612 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Symptomatic intracerebral hemorrhage among eligible warfarin-treated patients receiving intravenous tissue plasminogen activator for acute ischemic stroke. 20212195 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Intravenous thrombolysis for acute ischemic stroke: the phase IV data. 17903870 2007
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human The Interventional Management of Stroke (IMS) II Study. 17525387 2007
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human [Treatment with intravenous rt-PA in a general hospital context: A review of the Saint-Jean Hospital experience from Perpignan, France]. 17086147 2006
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human The ALIAS Pilot Trial: a dose-escalation and safety study of albumin therapy for acute ischemic stroke--II: neurologic outcome and efficacy analysis. 16809570 2006
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience. 16126134 2005
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human In acute ischemic stroke, are asymptomatic intracranial hemorrhages clinically innocuous? 15087567 2004
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study. 15017018 2004
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke: initial Israeli experience. 14986460 2004
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Predicting outcome in ischemic stroke: external validation of predictive risk models. 12511774 2003
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. 11940547 2002
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial. 12221155 2002
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Effect of intravenous recombinant tissue plasminogen activator on ischemic stroke lesion size measured by computed tomography. NINDS; The National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study Group. 11108748 2000
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Candidates for thrombolytic treatment in acute ischaemic stroke--where are our patients in Hong Kong? 10572812 1999
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Cost-effectiveness of tissue plasminogen activator for acute ischemic stroke. NINDS rt-PA Stroke Study Group. 9566367 1998
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Hemopericardium and cardiac tamponade after thrombolysis for acute ischemic stroke. 9633741 1998
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Total quality improvement method for reduction of delays between emergency department admission and treatment of acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. 9400355 1997
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Nursing management of acute complications following rt-PA in acute ischemic stroke. The NINDS rt-PA Stroke Study Group. 9479658 1997
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human A systems approach to immediate evaluation and management of hyperacute stroke. Experience at eight centers and implications for community practice and patient care. The National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study Group. 9259745 1997
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.310 Therapeutic disease CTD_human Tissue plasminogen activator for acute ischemic stroke. 7477192 1995