Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | Our result revealed IL-1B rs1143627-AA (OR = 1.98, p = 0.029) and rs16944-GG (OR = 2.01, p = 0.025) was associated with an increased risk of cervical cancer. | 31222982 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Our study aimed to evaluate the association between IL-1α (4845 G/T), IL-1β (-511C/T) and IL-1RN (VNTR) polymorphisms and risk of cervical cancer. | 25925136 | 2015 | ||||
|
0.090 | Biomarker | disease | BEFREE | No significant association of IL-1β-31T/C and cervical cancer risk was detected. | 24905619 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | A meta-analysis was conducted on the associations between the CTLA-4 +49 A/G, -318 C/T, IL-1B -511 C/T, and IL-1 receptor antagonist (IL-1RN) polymorphisms and cervical cancer.We included 15 studies on cervical cancer. | 24712845 | 2014 | ||||
|
0.090 | Biomarker | disease | BEFREE | The clinical relevance of our results was further confirmed in HPV-positive tissue samples, where a gradual decrease of IL-1β towards cervical cancer could be discerned. | 23935506 | 2013 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The plasma levels above the 75th percentile of controls (IL-1β ≥ 45.74 pg/ml) were significantly associated with a 2.49-fold increased risk of cervical cancer. | 21424904 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Genetic variants of interleukin-1RN and interleukin-1beta genes and risk of cervical cancer. | 18333945 | 2008 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | We assessed the association between the IL1B -511 polymorphism and cervical cancer risk in a hospital-based case-control study among 546 Korean women (182 cases; 364 age-matched controls). | 17297261 | 2007 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Several human ovarian and cervical cancer cell lines spontaneously express the icIL-1Ra. icIL-1Ra-expressing cells did not have altered growth characteristics or altered short term responses to IL-1 compared with icIL-1Ra-nonexpressing cells. | 7594609 | 1995 |