Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1834
Gene Symbol: DSPP
DSPP
0.010 AlteredExpression disease BEFREE Significantly high expression levels of MMP20 and DSPP were observed in the malignant breast, colon, prostate, thyroid, and cervical neoplasms compared with their benign and normal counterparts. 30932369 2019
Entrez Id: 9313
Gene Symbol: MMP20
MMP20
0.010 AlteredExpression disease BEFREE Significantly high expression levels of MMP20 and DSPP were observed in the malignant breast, colon, prostate, thyroid, and cervical neoplasms compared with their benign and normal counterparts. 30932369 2019
Entrez Id: 732253
Gene Symbol: TDRG1
TDRG1
0.010 AlteredExpression disease BEFREE This in vivo study proved that the down-regulation of lncRNA TDRG1 inhibited cervical tumor growth by regulating miR-330-5p/ELK1. 31539116 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.010 AlteredExpression disease BEFREE Our study corroborates the rationale that PD-L1 expression in cervical neoplasms has no impact on survival. 31191020 2019
Entrez Id: 3956
Gene Symbol: LGALS1
LGALS1
0.010 Biomarker disease BEFREE A chemosensitivity assay showed that the most effective polypore mushroom extract was the methanol extract of T. versicolor (strain It-1), which inhibited the growth of 6 various solid tumors (A-549 and SWi573 [lung], HBL-100 and T-47D [breast], HeLa [cervix], and WiDr [colon]) at concentrations below 45 μg · mL-1, with a concentration as low as 0.7-3.6 μg · mL-1 causing 50% reduction in the proliferation of cancer cells in lung and cervix tumors. 29604909 2018
Entrez Id: 3939
Gene Symbol: LDHA
LDHA
0.010 Biomarker disease BEFREE Nuclear lactate dehydrogenase A senses ROS to produce α-hydroxybutyrate for HPV-induced cervical tumor growth. 30356100 2018
Entrez Id: 51458
Gene Symbol: RHCG
RHCG
0.010 AlteredExpression disease BEFREE In vivo, we also found that RHCG over-expression reduced cervical tumor growth through the same signaling pathways as we found in vitro. 29852177 2018
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.010 Biomarker disease BEFREE The database for PET (or positron emission tomography or FDG or fluorodeoxyglucose) AND cervical cancer (or cervical tumor or cervical neoplasm or cervical carcinoma) AND recurrence or relapse was searched. 29189444 2018
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
0.010 AlteredExpression disease BEFREE TXNDC5 is a cervical tumor susceptibility gene that stimulates cell migration, vasculogenic mimicry and angiogenesis by down-regulating SERPINF1 and TRAF1 expression. 29207620 2017
Entrez Id: 81567
Gene Symbol: TXNDC5
TXNDC5
0.010 Biomarker disease BEFREE TXNDC5 is a cervical tumor susceptibility gene that stimulates cell migration, vasculogenic mimicry and angiogenesis by down-regulating SERPINF1 and TRAF1 expression. 29207620 2017
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
0.010 AlteredExpression disease BEFREE Genetic and epigenetic alterations affecting PARK-2 expression in cervical neoplasm among North Indian patients. 28631565 2017
Entrez Id: 28956
Gene Symbol: LAMTOR2
LAMTOR2
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 51639
Gene Symbol: SF3B6
SF3B6
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 115482693
Gene Symbol: H3P8
H3P8
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 10923
Gene Symbol: SUB1
SUB1
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 6280
Gene Symbol: S100A9
S100A9
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 11102
Gene Symbol: RPP14
RPP14
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 10263
Gene Symbol: CDK2AP2
CDK2AP2
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.010 Biomarker disease BEFREE Transforming growth factor β1 (TGF-β1) is a multifunctional cytokine that plays important roles in cervical tumor formation, invasion, progression, and metastasis. 27010470 2016
Entrez Id: 6427
Gene Symbol: SRSF2
SRSF2
0.010 Biomarker disease BEFREE SRSF2 depletion in W12 tumor cells resulted in increased apoptosis, decreased proliferation, and decreased colony formation, suggesting that SRSF2 has oncogenic functions in cervical tumor progression. 25717103 2015
Entrez Id: 6656
Gene Symbol: SOX1
SOX1
0.010 Biomarker disease BEFREE In this study, we analyzed the concordance and clinical performance of DNA methylation biomarker (PAX1, SOX1, and ZNF582) detection in self-collected vaginal samples and physician-collected cervical samples for the identification of cervical neoplasm. 25985991 2015
Entrez Id: 29122
Gene Symbol: PRSS50
PRSS50
0.010 GeneticVariation disease BEFREE Through overexpression experiments using both TSP50 and a TSP50 mutant (TSP50 T310A), it is clear that this protein may play an important role in carcinogenesis and progression of cervical tumor. 25312478 2015
Entrez Id: 6662
Gene Symbol: SOX9
SOX9
0.010 Biomarker disease BEFREE SOX9, a potential tumor suppressor in cervical cancer, transactivates p21WAF1/CIP1 and suppresses cervical tumor growth. 26036262 2015
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.010 Biomarker disease BEFREE SOX9, a potential tumor suppressor in cervical cancer, transactivates p21WAF1/CIP1 and suppresses cervical tumor growth. 26036262 2015
Entrez Id: 147948
Gene Symbol: ZNF582
ZNF582
0.010 Biomarker disease BEFREE In this study, we analyzed the concordance and clinical performance of DNA methylation biomarker (PAX1, SOX1, and ZNF582) detection in self-collected vaginal samples and physician-collected cervical samples for the identification of cervical neoplasm. 25985991 2015