Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.470 CausalMutation disease CGI
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.470 AlteredExpression disease LHGDN p53, Bcl-2, PCNA expression, and apoptotic rates during cervical tumorigenesis. 15033825 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.470 Biomarker disease BEFREE HPV18 E6 and E7 genes affect cell cycle, pRB and p53 of cervical tumor cells and represent prominent candidates for intervention by use peptide nucleic acids (PNAs). 15145519 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.470 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.470 GeneticVariation disease BEFREE The implication of the codon 72 polymorphism of p53 in cervical tumor remains controversial. 12821336 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.470 Biomarker disease LHGDN Relationship between HPV typing and abnormality of G1 cell cycle regulators in cervical neoplasm. 14675665 2003
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
0.010 AlteredExpression disease LHGDN Over-expression of topoisomerase IIalpha is related to the grade of cervical intraepithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict prognosis in cervical cancer or HPV clearance after cone treatment. 16990717 2006
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.020 Biomarker disease LHGDN Substantial changes in gene expression of Wnt, MAPK and TNFalpha pathways induced by TGF-beta1 in cervical cancer cell lines. 15878915 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.020 Biomarker disease BEFREE Association between Toll-like receptor and tumor necrosis factor immunological pathways in uterine cervical neoplasms. 28009429 2017
Entrez Id: 3371
Gene Symbol: TNC
TNC
0.010 Biomarker disease LHGDN Value of tenascin-C content and association with clinicopathological parameters in uterine cervical lesions. 12209613 2002
Entrez Id: 100302736
Gene Symbol: TMED7-TICAM2
TMED7-TICAM2
0.010 AlteredExpression disease BEFREE Increased expression of SKP2 and phospho-MAPK/ERK1/2 and decreased expression of p27 during tumor progression of cervical neoplasms. 17079005 2007
Entrez Id: 51014
Gene Symbol: TMED7
TMED7
0.010 AlteredExpression disease BEFREE Increased expression of SKP2 and phospho-MAPK/ERK1/2 and decreased expression of p27 during tumor progression of cervical neoplasms. 17079005 2007
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
0.020 AlteredExpression disease BEFREE Moreover, the highest level of TLR9 expression was significantly associated with a greater risk for developing squamous intraepithelial cervical lesion and uterine cervical neoplasm. 28819773 2017
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
0.020 Biomarker disease BEFREE Monocyte-derived Langerhans cells and cervical tumor LCs were stimulated with TLR7, TLR8, and TLR9 ligands. 23221735 2013
Entrez Id: 51284
Gene Symbol: TLR7
TLR7
0.010 Biomarker disease BEFREE Monocyte-derived Langerhans cells and cervical tumor LCs were stimulated with TLR7, TLR8, and TLR9 ligands. 23221735 2013
Entrez Id: 353376
Gene Symbol: TICAM2
TICAM2
0.010 AlteredExpression disease BEFREE Increased expression of SKP2 and phospho-MAPK/ERK1/2 and decreased expression of p27 during tumor progression of cervical neoplasms. 17079005 2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.010 Biomarker disease BEFREE Transforming growth factor β1 (TGF-β1) is a multifunctional cytokine that plays important roles in cervical tumor formation, invasion, progression, and metastasis. 27010470 2016
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.310 AlteredExpression disease LHGDN High expression of human telomerase reverse transcriptase in high-grade intraepithelial neoplasia and carcinoma of uterine cervix and its correlation with human papillomavirus infection. 17644806 2007
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.310 Biomarker disease CTD_human Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. 19151717 2009
Entrez Id: 732253
Gene Symbol: TDRG1
TDRG1
0.010 AlteredExpression disease BEFREE This in vivo study proved that the down-regulation of lncRNA TDRG1 inhibited cervical tumor growth by regulating miR-330-5p/ELK1. 31539116 2019
Entrez Id: 10923
Gene Symbol: SUB1
SUB1
0.010 PosttranslationalModification disease BEFREE Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms. 26655237 2016
Entrez Id: 6794
Gene Symbol: STK11
STK11
0.020 GeneticVariation disease BEFREE Here, we report a detailed analysis of a case of a cervical tumor in a PJS patient showing a large genomic deletion in exon 1 of STK11 without human papillomavirus infection. 24490603 2014
Entrez Id: 6794
Gene Symbol: STK11
STK11
0.020 Biomarker disease BEFREE LKB1 is thus a major cervical tumor suppressor, demonstrating that acquired genetic alterations drive progression of HPV-induced dysplasias to invasive, lethal cancers. 19340305 2009
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.310 Biomarker disease CTD_human Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cells. 25061499 2014
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.310 Biomarker disease BEFREE GRIM‑19‑mediated Stat3 activation is a determinant for resveratrol‑induced proliferation and cytotoxicity in cervical tumor‑derived cell lines. 25351437 2015