×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.470
CausalMutation
disease
CGI
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.470
AlteredExpression
disease
LHGDN
p53, Bcl-2, PCNA expression, and apoptotic rates during cervical tumorigenesis.
15033825
2003
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.470
Biomarker
disease
BEFREE
HPV18 E6 and E7 genes affect cell cycle, pRB and p53 of cervical tumor cells and represent prominent candidates for intervention by use peptide nucleic acids (PNAs).
15145519
2004
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.470
GeneticVariation
disease
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.470
GeneticVariation
disease
BEFREE
The implication of the codon 72 polymorphism of p53 in cervical tumor remains controversial.
12821336
2003
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.470
Biomarker
disease
LHGDN
Relationship between HPV typing and abnormality of G1 cell cycle regulators in cervical neoplasm.
14675665
2003
×
Entrez Id:
7153
Gene Symbol:
TOP2A
TOP2A
0.010
AlteredExpression
disease
LHGDN
Over-expression of topoisomerase IIalpha is related to the grade of cervical intraepithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict prognosis in cervical cancer or HPV clearance after cone treatment.
16990717
2006
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.020
Biomarker
disease
LHGDN
Substantial changes in gene expression of Wnt, MAPK and TNFalpha pathways induced by TGF-beta1 in cervical cancer cell lines.
15878915
2005
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.020
Biomarker
disease
BEFREE
Association between Toll-like receptor and tumor necrosis factor immunological pathways in uterine cervical neoplasms .
28009429
2017
×
Entrez Id:
3371
Gene Symbol:
TNC
TNC
0.010
Biomarker
disease
LHGDN
Value of tenascin-C content and association with clinicopathological parameters in uterine cervical lesions.
12209613
2002
TMED7-TICAM2
0.010
AlteredExpression
disease
BEFREE
Increased expression of SKP2 and phospho-MAPK/ERK1/2 and decreased expression of p27 during tumor progression of cervical neoplasms .
17079005
2007
×
Entrez Id:
51014
Gene Symbol:
TMED7
TMED7
0.010
AlteredExpression
disease
BEFREE
Increased expression of SKP2 and phospho-MAPK/ERK1/2 and decreased expression of p27 during tumor progression of cervical neoplasms .
17079005
2007
×
Entrez Id:
54106
Gene Symbol:
TLR9
TLR9
0.020
AlteredExpression
disease
BEFREE
Moreover, the highest level of TLR9 expression was significantly associated with a greater risk for developing squamous intraepithelial cervical lesion and uterine cervical neoplasm .
28819773
2017
×
Entrez Id:
54106
Gene Symbol:
TLR9
TLR9
0.020
Biomarker
disease
BEFREE
Monocyte-derived Langerhans cells and cervical tumor LCs were stimulated with TLR7, TLR8, and TLR9 ligands.
23221735
2013
×
Entrez Id:
51284
Gene Symbol:
TLR7
TLR7
0.010
Biomarker
disease
BEFREE
Monocyte-derived Langerhans cells and cervical tumor LCs were stimulated with TLR7 , TLR8, and TLR9 ligands.
23221735
2013
×
Entrez Id:
353376
Gene Symbol:
TICAM2
TICAM2
0.010
AlteredExpression
disease
BEFREE
Increased expression of SKP2 and phospho-MAPK/ERK1/2 and decreased expression of p27 during tumor progression of cervical neoplasms .
17079005
2007
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.010
Biomarker
disease
BEFREE
Transforming growth factor β1 (TGF-β1 ) is a multifunctional cytokine that plays important roles in cervical tumor formation, invasion, progression, and metastasis.
27010470
2016
×
Entrez Id:
7015
Gene Symbol:
TERT
TERT
0.310
AlteredExpression
disease
LHGDN
High expression of human telomerase reverse transcriptase in high-grade intraepithelial neoplasia and carcinoma of uterine cervix and its correlation with human papillomavirus infection.
17644806
2007
×
Entrez Id:
7015
Gene Symbol:
TERT
TERT
0.310
Biomarker
disease
CTD_human
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.
19151717
2009
×
Entrez Id:
732253
Gene Symbol:
TDRG1
TDRG1
0.010
AlteredExpression
disease
BEFREE
This in vivo study proved that the down-regulation of lncRNA TDRG1 inhibited cervical tumor growth by regulating miR-330-5p/ELK1.
31539116
2019
×
Entrez Id:
10923
Gene Symbol:
SUB1
SUB1
0.010
PosttranslationalModification
disease
BEFREE
Human papillomavirus types 16 E1 mRNA is transcribed from P14 early promoter in cervical neoplasms .
26655237
2016
×
Entrez Id:
6794
Gene Symbol:
STK11
STK11
0.020
GeneticVariation
disease
BEFREE
Here, we report a detailed analysis of a case of a cervical tumor in a PJS patient showing a large genomic deletion in exon 1 of STK11 without human papillomavirus infection.
24490603
2014
×
Entrez Id:
6794
Gene Symbol:
STK11
STK11
0.020
Biomarker
disease
BEFREE
LKB1 is thus a major cervical tumor suppressor, demonstrating that acquired genetic alterations drive progression of HPV-induced dysplasias to invasive, lethal cancers.
19340305
2009
×
Entrez Id:
6774
Gene Symbol:
STAT3
STAT3
0.310
Biomarker
disease
CTD_human
Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cells.
25061499
2014
×
Entrez Id:
6774
Gene Symbol:
STAT3
STAT3
0.310
Biomarker
disease
BEFREE
GRIM‑19‑mediated Stat3 activation is a determinant for resveratrol‑induced proliferation and cytotoxicity in cervical tumor ‑derived cell lines.
25351437
2015