Gene: MORC2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 22880
Gene Symbol: MORC2
MORC2 		0.360 GeneticVariation disease BEFREE To date, 31 families have been described with mutations in MORC2, indicating that this gene is frequently involved in axonal CMT cases. 30624633 2019
Entrez Id: 22880
Gene Symbol: MORC2
MORC2 		0.360 GeneticVariation disease BEFREE Missense mutations in MORC2 cause neuropathies including spinal muscular atrophy and Charcot-Marie-Tooth disease. 29440755 2018
Entrez Id: 22880
Gene Symbol: MORC2
MORC2 		0.360 GeneticVariation disease BEFREE These data define a critical role for MORC2 in epigenetic silencing by the HUSH complex and provide a mechanistic basis underpinning the role of MORC2 mutations in CMT disease. 28581500 2017
Entrez Id: 22880
Gene Symbol: MORC2
MORC2 		0.360 Biomarker disease CTD_human These data define a critical role for MORC2 in epigenetic silencing by the HUSH complex and provide a mechanistic basis underpinning the role of MORC2 mutations in CMT disease. 28581500 2017
Entrez Id: 22880
Gene Symbol: MORC2
MORC2 		0.360 GeneticVariation disease BEFREE As the second most common causative gene of CMT type 2 after MFN2, MORC2 variants were detected in 2.7% of patients with CMT type 2. 28771897 2017
Entrez Id: 22880
Gene Symbol: MORC2
MORC2 		0.360 GeneticVariation disease BEFREE MORC2 mutations cause axonal Charcot-Marie-Tooth disease with pyramidal signs. 26659848 2016
Entrez Id: 22880
Gene Symbol: MORC2
MORC2 		0.360 GeneticVariation disease BEFREE Here we present a new axonal Charcot-Marie-Tooth disease form, associated with the gene microrchidia family CW-type zinc finger 2 (MORC2). 26497905 2016