Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease BEFREE Our results confirm UGT1A1 (TA)7 allele as one of the factors accounting for the hyperbilirubinemia and cholelithiasis observed in SCA and bTH. 24204915 2013
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease GWASDB A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. 22558097 2012
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease GWASCAT A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. 22558097 2012
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 Biomarker disease BEFREE Patients with co-existing hereditary spherocytosis (HS) and UDP-glucuronosyltransferase 1A1 (UGT1A1) deficiency as Gilbert's syndrome (GS) have been reported, and previous studies have demonstrated an increased risk for developing gallstones in patients with co-inheritance of GS and HS. 21319362 2011
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease BEFREE Cholelithiasis has a remarkable frequency and precocity in patients with TM and especially in those with (TA)(7)/(TA)(7) UGT1-A1 genotype. 19021734 2009
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease BEFREE Recent studies have shown that a variant TATA-box in the promoter region of the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene is associated with the development of cholelithiasis. 18081723 2008
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease BEFREE To test the hypothesis that the variant UDP-glucuronosyltransferase 1A1 (UGT1A1) gene, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and thalassemia influence bilirubin metabolism and play a role in the development of cholelithiasis. 16237771 2005
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease BEFREE Among the control group, the prevalence of gallstones did not differ significantly in relation to UGT1-A1 genotype, while in women carriers of beta-thalassemia it increased in an allele dose-dependent fashion. 14555305 2003
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 GeneticVariation disease BEFREE Its incidence was higher (P < 0.05) in patients homozygous for the (TA7) motif in the promoter of the UGT1-A1 gene, the genotype associated with Gilbert's syndrome, which seems to be a risk factor for the development of gallstones in TM and TI patients. 11843828 2001
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6
0.180 Biomarker disease BEFREE These results suggest that the UGT*1 genotpe is of importance in the genesis of gallstones in this population of patients. 11425418 2001