Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | group | BEFREE | The results thus link the expression of CD30, which serves as a marker for HTLV-1 disease status, to an active proliferating cell fraction featuring polylobation and chromosomal aberrations. | 30068708 | 2018 | ||||
|
0.070 | Biomarker | group | BEFREE | The lymphoma was partially positive for CD30, diffusely positive for EBV by in situ hybridization, and clonal for T-cell receptor gene rearrangement and cytogenetic abnormalities. | 18237230 | 2008 | ||||
|
0.070 | Biomarker | group | BEFREE | Cytogenetic abnormalities that could play a role in CD30+ CTCL tumour pathogenesis and relapses remain unknown. | 14595754 | 2003 | ||||
|
0.070 | Biomarker | group | BEFREE | Morphologically normal, CD30-negative B-lymphocytes with chromosome aberrations in classical Hodgkin's disease: the progenitor cell of the malignant clone? | 10629553 | 1999 | ||||
|
0.070 | GeneticVariation | group | BEFREE | A case with a complex chromosome abnormality with a t(2;2)(p23;q23) in CD30+/Ki-1+ anaplastic large cell lymphoma (ALCL) is described. | 9613994 | 1998 | ||||
|
0.070 | AlteredExpression | group | BEFREE | The cell line exhibited the typical features of a lymphoblastoid cell line (LCL): (1) growth pattern in large clumps, (2) lack of structural chromosome abnormalities, (3) type III latency with expression of EBV-associated EBNA2 and LMP, as well as B cell activation markers CD23 and CD30, thereby showing characteristics of an EBV producer cell line, i.e. a latent infection with a small subpopulation of cells spontaneously entering the lytic cycle, (4) inducibility of the lytic cycle by IdU and TPA, leading to an increase of early antigen and viral capsid antigen-positive cells from 1 to 15-20%, and (5) elimination of the linear viral genomes by treatment with acyclovir (ACV), without affecting the circular episomal genomes. | 8876615 | 1996 | ||||
|
0.070 | GeneticVariation | group | BEFREE | Morphology in Ki-1(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35). | 2157342 | 1990 |