Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4548
Gene Symbol: MTR
MTR 		0.310 Biomarker disease CTD_human Folate pathway and nonsyndromic cleft lip and palate. 21254359 2011
Entrez Id: 9935
Gene Symbol: MAFB
MAFB 		0.310 Biomarker disease CTD_human SNPs near two genes not previously associated with cleft lip with and without cleft palate (MAFB, most significant SNP rs13041247, with odds ratio (OR) per minor allele = 0.704, 95% CI 0.635-0.778, P = 1.44 x 10(-11); and ABCA4, most significant SNP rs560426, with OR = 1.432, 95% CI 1.292-1.587, P = 5.01 x 10(-12)) and two previously identified regions (at chromosome 8q24 and IRF6) attained genome-wide significance. 20436469 2010
Entrez Id: 2255
Gene Symbol: FGF10
FGF10 		0.310 Biomarker disease CTD_human Sequence evaluation of FGF and FGFR gene conserved non-coding elements in non-syndromic cleft lip and palate cases. 17963255 2007
Entrez Id: 2252
Gene Symbol: FGF7
FGF7 		0.310 Biomarker disease CTD_human Sequence evaluation of FGF and FGFR gene conserved non-coding elements in non-syndromic cleft lip and palate cases. 17963255 2007
Entrez Id: 2248
Gene Symbol: FGF3
FGF3 		0.310 Biomarker disease CTD_human Sequence evaluation of FGF and FGFR gene conserved non-coding elements in non-syndromic cleft lip and palate cases. 17963255 2007
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		0.310 Biomarker disease CTD_human Sequence evaluation of FGF and FGFR gene conserved non-coding elements in non-syndromic cleft lip and palate cases. 17963255 2007
Entrez Id: 6948
Gene Symbol: TCN2
TCN2 		0.310 Biomarker disease CTD_human Study of four genes belonging to the folate pathway: transcobalamin 2 is involved in the onset of non-syndromic cleft lip with or without cleft palate. 16470748 2006
Entrez Id: 144100
Gene Symbol: PLEKHA7
PLEKHA7 		0.300 Biomarker disease GENOMICS_ENGLAND Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate. 29805042 2018
Entrez Id: 80004
Gene Symbol: ESRP2
ESRP2 		0.300 Biomarker disease GENOMICS_ENGLAND Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate. 29805042 2018
Entrez Id: 54477
Gene Symbol: PLEKHA5
PLEKHA5 		0.300 Biomarker disease GENOMICS_ENGLAND Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate. 29805042 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.300 Biomarker disease CTD_human Long-range enhancers regulating Myc expression are required for normal facial morphogenesis. 24859337 2014
Entrez Id: 10588
Gene Symbol: MTHFS
MTHFS 		0.300 Biomarker disease CTD_human Folate pathway and nonsyndromic cleft lip and palate. 21254359 2011
Entrez Id: 23743
Gene Symbol: BHMT2
BHMT2 		0.300 Biomarker disease CTD_human Folate pathway and nonsyndromic cleft lip and palate. 21254359 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker disease CTD_human Folate pathway and nonsyndromic cleft lip and palate. 21254359 2011
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.300 Biomarker disease CTD_human Sequence evaluation of FGF and FGFR gene conserved non-coding elements in non-syndromic cleft lip and palate cases. 17963255 2007
Entrez Id: 10253
Gene Symbol: SPRY2
SPRY2 		0.300 Biomarker disease CTD_human Stage-dependent craniofacial defects resulting from Sprouty2 overexpression. 17576140 2007
Entrez Id: 2254
Gene Symbol: FGF9
FGF9 		0.300 Biomarker disease CTD_human Sequence evaluation of FGF and FGFR gene conserved non-coding elements in non-syndromic cleft lip and palate cases. 17963255 2007
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		0.300 Biomarker disease CTD_human Sequence evaluation of FGF and FGFR gene conserved non-coding elements in non-syndromic cleft lip and palate cases. 17963255 2007
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11 		0.300 Biomarker disease GENOMICS_ENGLAND A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse. 17035249 2006
Entrez Id: 7055
Gene Symbol: THAS
THAS 		0.300 Biomarker disease CTD_human X-linked midline defects. 4039891 1985
Entrez Id: 7021
Gene Symbol: TFAP2B
TFAP2B 		0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 340419
Gene Symbol: RSPO2
RSPO2 		0.300 Biomarker disease GENOMICS_ENGLAND