| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.390 | GeneticVariation | disease | BEFREE | Association between methylenetetrahydrofolate reductase polymorphisms and non-syndromic cleft lip with or without palate susceptibility: an updated systematic review and meta-analysis. | 31303355 | 2019 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | This integrated analysis supports the previous finding of differences in DNA methylation across the two sides of cleft lip and further suggests a possible role of MTHFR c.677C>T genotype in establishing this difference. | 31161688 | 2019 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | We revealed statistically association between the MTHFR C677T gene polymorphism and nonsyndromic cleft lip and/or palate in the Turkish population. | 23725631 | 2013 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | On the contrary, MTHFR 1298 AC and 1298 AC/CC appeared to be protective against cleft lip with cleft palate. | 21612398 | 2011 | ||||
|
0.390 | GeneticVariation | disease | LHGDN | Folate and clefts of the lip and palate--a U.K.-based case-control study: Part II: Biochemical and genetic analysis. | 18616362 | 2008 | ||||
|
0.390 | Biomarker | disease | CTD_human | Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. | 16470725 | 2006 | ||||
|
0.390 | GeneticVariation | disease | LHGDN | Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. | 16470725 | 2006 | ||||
|
0.390 | GeneticVariation | disease | LHGDN | Maternal 677CT/1298AC genotype of the MTHFR gene as a risk factor for cleft lip. | 12746418 | 2003 | ||||
|
0.390 | GeneticVariation | disease | LHGDN | Maternal MTHFR genotype contributes to the risk of non-syndromic cleft lip and palate. | 12011160 | 2002 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip. | 9843036 | 1998 |