Myeloid ecotropic insertion site 2 (MEIS2) gene, encoding a homeodomain-containing transcription factor, has been recently related to syndromic intellectual disability with cleft palate and cardiac defects.
We confirm and extend a recent single clinical report stating that deletions in MEIS2 can cause cleft palate [Crowley et al.(2010); Am J Med Genet 152A:1326-1327].