Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.530 Biomarker disease BEFREE These activated inflammatory mediators and pathology of colitis were completely suppressed by treatment with a NO scavenger, 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, as well as an iNOS inhibitor, aminoguanidine. 24992835 2014
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.530 AlteredExpression disease BEFREE Analysis of human biopsies of colitis and colon cancer using immunohistochemistry revealed elevated iNOS protein expression levels, which were strongly paralleled by increased expression of nitrotyrosine suggesting that iNOS has been highly activated in these tissues. 22417974 2012
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.530 Biomarker disease BEFREE NO increases WISP-1 expression both in vitro and in vivo, suggesting a new role for iNOS and NO in colitis. 19238344 2009
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.530 Biomarker disease CTD_human Resistance to DSS-induced colitis was lost when wild-type (wt) BM was used to reconstitute iNOS-/- mice. 17449036 2007
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.530 Biomarker disease RGD Expression of iNOS mRNA associated with suppression of colonic contraction in rat colitis. 16866779 2006
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.530 Biomarker disease CTD_human Colitis and interleukin 1beta up-regulate inducible nitric oxide synthase and superoxide dismutase in rat myenteric neurons. 8698225 1996