Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 124626
Gene Symbol: ZPBP2
ZPBP2 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 128611
Gene Symbol: ZNF831
ZNF831 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 58492
Gene Symbol: ZNF77
ZNF77 		0.010 Biomarker disease BEFREE Tripeptide K(D)PT Is Well Tolerated in Mild-to-moderate Ulcerative Colitis: Results from a Randomized Multicenter Study. 28092306 2017
Entrez Id: 65251
Gene Symbol: ZNF649
ZNF649 		0.010 Biomarker disease BEFREE We detected SNPs at HLA-DRB1, and African-specific SNPs at ZNF649 and LSAMP, with associations of genome-wide significance for UC. 27693347 2017
Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410 		0.010 GeneticVariation disease BEFREE In contrast, the other three VDR gene polymorphisms (Apa I, Taq I and Fok I) were not associated with UC susceptibility in the Han Chinese cohort. 21401893 2011
Entrez Id: 22891
Gene Symbol: ZNF365
ZNF365 		0.110 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 22891
Gene Symbol: ZNF365
ZNF365 		0.110 Biomarker disease BEFREE The SNPs tagging the PTGER4, NKX2-3, ZNF365, IFNG, PSMG1, and HLA area were associated with UC (P values 0.047 to 4×10(-5)). 21818367 2011
Entrez Id: 91975
Gene Symbol: ZNF300
ZNF300 		0.100 GeneticVariation disease GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
Entrez Id: 23528
Gene Symbol: ZNF281
ZNF281 		0.010 AlteredExpression disease BEFREE ZNF281 expression correlates with the disease severity degree of CD and UC patients. 30619271 2018
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1 		0.110 AlteredExpression disease BEFREE Consistent with epidemiologic predictions, many IBD-associated loci demonstrate genome-wide significant associations to both CD and UC, notably, genes whose products function in the interleukin-23 pathway, and transcription factors, including NK2 transcription factor related, locus 3 (NKX2-3), SMAD3, STAT3, ZMIZ1, and c-REL. 21530736 2011
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1 		0.110 GeneticVariation disease GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1 		0.110 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 84619
Gene Symbol: ZGPAT
ZGPAT 		0.100 GeneticVariation disease GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90 		0.110 GeneticVariation disease GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90 		0.110 GeneticVariation disease GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90 		0.110 GeneticVariation disease GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90 		0.110 GeneticVariation disease GWASDB Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. 19915572 2009
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90 		0.110 GeneticVariation disease GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90 		0.110 GeneticVariation disease BEFREE We identified genes that might be truly causative, but GWAS might have failed to identify for 148 out of the GWAS-identified SNPs; for example, TUFM (P = 3.3E-48) was identified for inflammatory bowel disease (early onset); ZFP90 (P = 4.4E-34) for ulcerative colitis; and IDUA (P = 2.2E-11) for Parkinson's disease. 24956270 2014
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90 		0.110 GeneticVariation disease GWASCAT Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. 19915572 2009
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1 		0.010 Biomarker disease BEFREE ZEB1 was induced in the colonic epithelium of UC and of mouse models of colitis. 31366457 2019
Entrez Id: 7704
Gene Symbol: ZBTB16
ZBTB16 		0.010 Biomarker disease BEFREE FOS and SOCS3 were identified as candidate genes for CD and other three genes HELB, ZBTB16 and FAM107A were candidate genes for UC. 25182475 2014
Entrez Id: 81030
Gene Symbol: ZBP1
ZBP1 		0.020 Biomarker disease BEFREE A mouse UC model was successfully constructed based on scores of DAI, colonic damage and pathological lesions under the microscope. 31378906 2019
Entrez Id: 81030
Gene Symbol: ZBP1
ZBP1 		0.020 AlteredExpression disease BEFREE Then, the immunological effects of the MAP vaccine were assessed in vitro and in vivo, as well as its impacts on DAI index, serum DAO levels, colon tissue tight junction protein amounts, ultrastructural changes, and MPO activity in BALB/c mice with UC. 31524230 2019
Entrez Id: 7535
Gene Symbol: ZAP70
ZAP70 		0.010 GeneticVariation disease BEFREE These results suggest the involvement of the ZAP70 and PTPN6 genes in the genetic component conferring a general susceptibility to CD and UC, respectively. 23406209 2013