Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 GeneticVariation disease BEFREE IRF5 genetic variants leading to decreased IRF5 expression reduce risk for ulcerative colitis. 31053739 2019
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 GeneticVariation disease BEFREE We confirmed the associations of 10 known UC risk loci in Koreans: rs76418789 in IL23R (combined P = 1.25 × 10), rs4728142 in IRF5 (combined P = 3.17 × 10), rs1830610 near JAK2 (combined P = 2.28 × 10), rs1555791 near TNFRSF14 (combined P = 1.62 × 10), rs880790 between IL10-IL19 (combined P = 3.73 × 10), rs10185424 between IL1R2-IL1R1 (combined P = 1.54 × 10), rs6478108 in TNFSF15 (combined P = 9.28 × 10), rs861857 between UBE2L3-YDJC (combined P = 3.05 × 10), rs1801274 in FCGR2A (discovery P = 1.54 × 10), and rs17085007 between GPR12-USP12 (discovery P = 3.64 × 10). 26398853 2016
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 Biomarker disease BEFREE The only observed association with UC was for IRF5. 23971939 2013
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 GeneticVariation disease BEFREE IRF5 polymorphisms contribute to the risk profile for Crohn's disease and ulcerative colitis along with ancestry and NOD2 genotypes. 22257839 2012
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 Biomarker disease BEFREE Twelve polymorphisms in the CREM, STAT4, STAT5a, Stat5b, and IRF5 genes were genotyped in a cohort of 107 IBD patients (39 Crohn's disease [CD] and 68 ulcerative colitis [UC]) and 162 controls from southern Tunisia. 22019623 2011
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 Biomarker disease CTD_human Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. 21297633 2011
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 PosttranslationalModification disease BEFREE IRF5 promoter methylation in association to disease state was assessed in 87 proband (49 healthy, 18 Crohn's disease, 20 ulcerative colitis) PBL samples. 20127100 2010
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 GeneticVariation disease BEFREE We studied whether the IRF5 gene is also associated with inflammatory bowel diseases (IBD), Crohn disease (CD) and ulcerative colitis (UC). 17881657 2007
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.570 Biomarker disease GENOMICS_ENGLAND