Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease GWASCAT A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis. 25082827 2014
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 Biomarker disease BEFREE We found 14 SNPs tagging 9 loci, including 21q21.1, NKX2-3, MST1, the HLA region, 1p36.13, IL10, JAK2, ORMDL3, and IL23R, to be associated with UC. 23974994 2013
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease BEFREE A non-synonymous coding variant in MSP (689C) has been associated with genetic susceptibility to both Crohn's disease and ulcerative colitis, two major types of inflammatory bowel disease (IBD) characterized by chronic inflammation of the digestive tract. 24409221 2013
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease BEFREE Colon-only CD (n = 228) was compared with healthy controls: three of six UC SNPs (in MST1, HLA-DRA, and IL-23R) and 11 of 34 CD SNPs: in IRGM, NOD2 (rs2066845), CCNY, MST1, IL23R, PTPN22, C11orf30, ZNF365, PTPN2, PSMG1, and rs1456893 were significantly associated. 21830272 2011
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease GWASCAT Genome-wide association identifies multiple ulcerative colitis susceptibility loci. 20228799 2010
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease GWASDB Genome-wide association identifies multiple ulcerative colitis susceptibility loci. 20228799 2010
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 Biomarker disease CTD_human Genome-wide association identifies multiple ulcerative colitis susceptibility loci. 20228799 2010
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease BEFREE BSN and MST1 were significantly associated with either CD (P(rs9858542) 2.5 x 10(-7); P(rs3197999) 3.9 x 10(-7)), and UC (P(rs9858542) = 3.1 x 10(-4); P(rs3197999) = 8 x 10(-4)). 20024904 2010
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease BEFREE Genome-wide studies highlighted the effect in Crohn's disease (CD) and ulcerative colitis (UC) susceptibility of single nucleotide polymorphisms (SNPs) in 3p21, where BSN (bassoon), MST1 (macrophage stimulating-1) and MST1R (MST1 Receptor) genes map. 19657358 2009
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 GeneticVariation disease BEFREE We then identified a non-synonymous coding variant (rs3197999, R689C) in the macrophage-stimulating 1 (MST1) gene (P-value 3.62 x 10(-6)) that accounts for the association signal, and shows association with both CD and UC. 19079170 2008
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 AlteredExpression disease LHGDN Five mucosal transcripts of interest in ulcerative colitis identified by quantitative real-time PCR: a prospective study. 18700007 2008
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 Biomarker disease CTD_human We also show that several risk loci are common to ulcerative colitis and Crohn's disease (IL23R, IL12B, HLA, NKX2-3 and MST1), whereas autophagy genes ATG16L1 and IRGM, along with NOD2 (also known as CARD15), are specific for Crohn's disease. 18438406 2008
Entrez Id: 4485
Gene Symbol: MST1
MST1
0.470 Biomarker disease HPO