Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.010 Biomarker group BEFREE A first-degree relative (FDR) with thyroid disease increased the risk for TPOAb (OR: 2.4, <i>p</i> = 0.03) and both autoantibodies (OR: 2.6, <i>p</i> = 0.03), a FDR or sibling with celiac disease increased the risk for both autoantibodies (OR: 3.7, <i>p</i> = 0.03, and OR: 4.8, <i>p</i> = 0.003), a FDR or sibling with diabetes increased the risk for thyroid autoantibody (OR: 3.0, <i>p</i> = 0.01, and OR: 5.4, <i>p</i> = 0.032), and a father with rheumatic disease increased the risk for TPOAb (OR: 15.2, <i>p</i> = 0.017), TGAb (OR: 11.3, <i>p</i> = 0.029), any autoantibody (OR: 9.6, <i>p</i> = 0.038), and both autoantibodies (OR: 20, <i>p</i> = 0.01). 29234623 2017