| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.530 | AlteredExpression | group | BEFREE | Here, we found that circular RNA (circCTIC1) was highly expressed in colon tumor and colon TICs. circCTIC1 knockdown impaired the self-renewal of colon TICs, and its overexpression played an opposite role. circCTIC1 promoted the expression of c-Myc and drove the self-renewal of colon TIC through c-Myc-dependent manner. circCTIC1 interacted with nuclear remodeling factor (NURF) complex, recruited NURF complex onto c-Myc promoter and finally drove the transcriptional initiation of c-Myc. | 30403769 | 2019 | ||||
|
0.530 | Therapeutic | group | RGD | MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. | 22641368 | 2012 | ||||
|
0.530 | Biomarker | group | CTD_human | Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate. | 21081470 | 2011 | ||||
|
0.530 | Biomarker | group | CTD_human | Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat. | 18283038 | 2008 | ||||
|
0.530 | AlteredExpression | group | LHGDN | Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc. | 16543245 | 2006 | ||||
|
0.530 | Biomarker | group | CTD_human | Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | 15059925 | 2004 | ||||
|
0.530 | AlteredExpression | group | BEFREE | Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression. | 11848471 | 2002 | ||||
|
0.530 | Biomarker | group | CTD_human | Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents. | 12189186 | 2002 |