×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
Therapeutic
group
CTD_human
Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone.
20540935
2010
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
AlteredExpression
group
BEFREE
Importantly, p21(WAF1/cip1) and peroxisome proliferator-activated receptor-gamma expression were absent in colon tumors from sulindac-treated mice, suggesting that loss of these proteins is necessary for drug resistance.
20716632
2010
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
Biomarker
group
LHGDN
Down-regulation of X-linked inhibitor of apoptosis synergistically enhanced peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition in colon cancer.
18645029
2008
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
Biomarker
group
LHGDN
PPARgamma1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells.
18203887
2008
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
Biomarker
group
LHGDN
Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma.
18608213
2008
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
AlteredExpression
group
LHGDN
Bitter gourd (Momordica charantia): a potential mechanism in anti-carcinogenesis of colon.
17461486
2007
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
Biomarker
group
LHGDN
Peroxisome proliferator-activated receptor gamma: a common link for non-alcoholic fatty liver disease and colorectal cancer?
17482764
2007
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
AlteredExpression
group
LHGDN
Low expression of ORF4, a dominant negative variant of peroxisome proliferator-activated receptor gamma, in colorectal adenocarcinoma.
17611675
2007
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
GeneticVariation
group
BEFREE
Colon cancer cases also were less likely to have a tumor with MSI if they had the PA or AA PPARgamma genotype (OR 0.68; 95% CI: 0.47-0.98); differences in Ki-ras mutations were not seen in colon tumors by PPARgamma genotype.
16489531
2006
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
GeneticVariation
group
LHGDN
Interactions of peroxisome proliferator-activated receptor {gamma} and diet in etiology of colorectal cancer.
15894676
2005
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
AlteredExpression
group
LHGDN
Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer.
14506281
2003
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
GeneticVariation
group
BEFREE
Acromegalic patients have an increased prevalence of colonic neoplasms and lower peroxisome proliferator-activated receptor gamma (PPARgamma ) levels, the latter acting as a tumor suppressor gene.
12915690
2003
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.400
AlteredExpression
group
BEFREE
Acromegalic patients have an increased prevalence of colonic neoplasms and lower PPARgamma levels in the colonic mucosa.
15008240
2003