The overexpression of four lipid metabolism-related genes (<i>ABCA1, ACSL1, AGPAT1</i> and <i>SCD</i> genes) has been proposed as prognostic marker of stage II CRC (ColoLipidGene signature).
ABCA1 is significantly overexpressed in patients at advanced stages of colorectal cancer, and its overexpression confers proliferative advantages together with caveolin-1 dependent-increased migratory and invasive capacities.