Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 AlteredExpression disease BEFREE Further, high KLF5 expression was observed in BRAF-mutant colorectal cancer. 30478887 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 GeneticVariation disease GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 GeneticVariation disease GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 Biomarker disease CTD_human Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 GeneticVariation disease BEFREE These findings raise a potentially oncogenic role for the P301S KLF5 mutant in colorectal cancer. 24398687 2014
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 Biomarker disease BEFREE Given that activation of the Wnt/β-catenin pathway is the most frequently altered pathway in human colorectal cancer, our results argue that KLF5 acts as a fundamental core regulator of intestinal oncogenesis at the stem-cell level, and they suggest KLF5 targeting as a rational strategy to eradicate stem-like cells in colorectal cancer. 24626089 2014
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 AlteredExpression disease BEFREE Both of these compounds, and two newly synthesized structural analogs of CID 5951923, significantly reduced endogenous KLF5 protein levels and decreased viability of several colorectal cancer cell lines without any apparent impact on IEC-6 cells. 21885866 2011
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.640 GeneticVariation disease UNIPROT