| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.430 | GeneticVariation | group | GWASCAT | A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. | 25990418 | 2015 | ||||
|
0.430 | GeneticVariation | group | GWASCAT | Association analyses identify 31 new risk loci for colorectal cancer susceptibility. | 31089142 | 2019 | ||||
|
0.430 | Biomarker | group | CTD_human | Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. | 18084292 | 2008 | ||||
|
0.430 | GeneticVariation | group | GWASCAT | Discovery of common and rare genetic risk variants for colorectal cancer. | 30510241 | 2019 | ||||
|
0.430 | Biomarker | group | CTD_human | Discovery of common and rare genetic risk variants for colorectal cancer. | 30510241 | 2019 | ||||
|
0.430 | AlteredExpression | group | BEFREE | Hereditary mixed polyposis syndrome (HMPS) is characterized by the development of mixed-morphology colorectal tumors and is caused by a 40-kb genetic duplication that results in aberrant epithelial expression of the gene encoding mesenchymal bone morphogenetic protein antagonist, GREM1. | 25419707 | 2015 | ||||
|
0.430 | GeneticVariation | group | GWASCAT | Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. | 24737748 | 2014 | ||||
|
0.430 | GeneticVariation | group | GWASCAT | Novel Common Genetic Susceptibility Loci for Colorectal Cancer. | 29917119 | 2019 | ||||
|
0.430 | GeneticVariation | group | BEFREE | The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors. | 25131200 | 2014 | ||||
|
0.430 | AlteredExpression | group | BEFREE | This model might be used to study progression of human colorectal tumors with RSPO fusion gene and GREM1 overexpression. | 31622618 | 2020 |