Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC
0.900 GeneticVariation group UNIPROT
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 Biomarker group CTD_human
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
0.410 Biomarker group CTD_human
Entrez Id: 207
Gene Symbol: AKT1
AKT1
0.350 Biomarker group CTD_human
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
0.330 Biomarker group CTD_human
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
0.330 Biomarker group CTD_human
Entrez Id: 201163
Gene Symbol: FLCN
FLCN
0.310 Biomarker group CTD_human
Entrez Id: 6714
Gene Symbol: SRC
SRC
0.310 Biomarker group CTD_human
Entrez Id: 699
Gene Symbol: BUB1
BUB1
0.310 Biomarker group CTD_human
Entrez Id: 79695
Gene Symbol: GALNT12
GALNT12
0.310 Biomarker group CTD_human
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
0.300 Biomarker group CTD_human
Entrez Id: 10395
Gene Symbol: DLC1
DLC1
0.300 Biomarker group CTD_human
Entrez Id: 2033
Gene Symbol: EP300
EP300
0.300 Biomarker group CTD_human
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.270 Biomarker group MGD
Entrez Id: 324
Gene Symbol: APC
APC
0.900 GeneticVariation group CLINVAR "APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""." 10737795 2000
Entrez Id: 2191
Gene Symbol: FAP
FAP
0.030 AlteredExpression group LHGDN 'Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer'. 16196122 2005
Entrez Id: 3791
Gene Symbol: KDR
KDR
0.310 Therapeutic group CTD_human (-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells. 20346928 2010
Entrez Id: 2810
Gene Symbol: SFN
SFN
0.020 Biomarker group LHGDN 14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients. 15867223 2005
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
0.380 Biomarker group LHGDN 15-hydroxy-eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator-activated receptor gamma-dependent pathway. 14566836 2003
Entrez Id: 324
Gene Symbol: APC
APC
0.900 Biomarker group CTD_human 4-Hydroxy-2(E)-nonenal metabolism differs in Apc(+/+) cells and in Apc(Min/+) cells: it may explain colon cancer promotion by heme iron. 21967605 2011
Entrez Id: 5270
Gene Symbol: SERPINE2
SERPINE2
0.010 AlteredExpression group BEFREE 5- Finally, Q-PCR analyses demonstrated that mRNA levels of serpinE2 were markedly increased in human adenomas in comparison to healthy adjacent tissues and in colorectal tumors, regardless of tumor stage and grade. 20942929 2010
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Therapeutic group CTD_human 5-Fluorouracil-interferon-alpha 2b adjuvant treatment of Dukes C colorectal cancer. 8026229 1994
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.500 GeneticVariation group BEFREE Colorectal tumors frequently contain activating mutations in KRAS. 16707468 2006
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.100 GeneticVariation group BEFREE Colorectal tumors with no (n = 68) and low-level (n = 18) MSI of patients clinically suspected of HNPCC were compared to colorectal tumors with high-level MSI (n = 12) of patients that carry a pathogenic germline mutation in a MMR gene. 16980941 2006
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.040 AlteredExpression group BEFREE Colorectal tumors that express a high level of miR-21 display reduced hMSH2 protein expression. 21078976 2010