Gene: TP53 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group LHGDN Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. 18419600 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE Clonal analysis of colorectal tumors using K-ras and p53 gene mutations as markers. 8634782 1995
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE Potential false-positive results with antigen enhancement for immunohistochemistry of the p53 gene product in colorectal neoplasms. 8778330 1996
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE There has been few reports describing that the prognostic significance of p53 alteration in colorectal tumors depended on the site of origin. 11295071 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 AlteredExpression group BEFREE Fhit, Mlh1, P53 and phenotypic expression in the early stage of colorectal neoplasms. 18097574 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group LHGDN Colorectal carcinomas from Middle East. Molecular and tissue microarray analysis of genomic instability pathways. 18176677 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE These observations suggest that p53 gene mutations are involved in flat-type as well as polypoid-type colorectal tumors at relatively later stages of carcinogenesis and that TGGE seems to be useful as one of the rapid screening methods. 8082516 1994
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human The predictive value of p53 and p33(ING1b) in patients with Dukes'C colorectal cancer. 17949449 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group LHGDN Expression of p53 in colorectal carcinoma: correlation with clinicopathologic features. 17198452 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE Combined inactivation of the microRNA 34a gene (MIR34A, by methylation) and the TP53 gene (by mutation or deletion) is observed in 50% of colorectal tumors that progress to distant metastases. 30099074 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group LHGDN Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan. 15041737 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 AlteredExpression group LHGDN Abberant crypt foci -- importance in colorectal carcinogenesis and expression of p53 and mdm2: a changing concept. 18080767 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 PosttranslationalModification group BEFREE To study the relevance of defective MGMT function by aberrant methylation in relation to the presence of p53 mutations, we studied 314 colorectal tumors for MGMT promoter hypermethylation and p53 mutational spectrum. 11406538 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE Tumor material was analyzed for p53 mutations in primary colorectal tumors and subsequent liver metastases from 41 consecutive patients who were scheduled to undergo surgical liver resection. 11241240 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 AlteredExpression group LHGDN Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis. 19016757 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group BEFREE Our data directly suggest that overexpression of CD95L by the wild-type p53 gene transfer induces neutrophil infiltration into human colorectal tumors, which may play a critical role in the bystander effect of p53 gene therapy. 11067949 2000
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group LHGDN The differentially mutational spectra of the APC, K-ras, and p53 genes in sporadic colorectal cancers from Taiwanese patients. 18265644 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE TP53 was the most commonly mutated gene, with prevalence similar to that of sporadic colorectal tumors (63% of cases). 26764183 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group LHGDN Mad2 and p53 expression profiles in colorectal cancer and its clinical significance. 12970887 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group LHGDN We have analyzed the prevalence of MDM2 gene amplifications and SNP309 in 284 colorectal tumors using a relatively new highly sensitive PCR/ligase detection reaction method in relation to TP53 mutational status and genomic instability. 18314481 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE Heme iron intake was associated with an increased risk of colorectal tumors harboring G>A transitions in KRAS and APC and overexpression of P53. 23983135 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group LHGDN Mutations in TP53 are a prognostic factor in colorectal hepatic metastases undergoing surgical resection. 17259658 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. 21946351 2011