Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE In this report, we compared the mutation patterns of the p53 gene in human colorectal tumors from Japanese patients with those from US patients. 1488746 1992
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 GeneticVariation group BEFREE These data provide strong evidence that mutations of the APC gene play a major role in the early development of colorectal neoplasms. 1528264 1992
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 GeneticVariation group CLINVAR APC mutations occur early during colorectal tumorigenesis. 1528264 1992
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group MGD The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system. 1541640 1992
Entrez Id: 374
Gene Symbol: AREG
AREG 		0.020 Biomarker group BEFREE Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors. 1596904 1992
Entrez Id: 4163
Gene Symbol: MCC
MCC 		0.040 GeneticVariation group BEFREE The MCC gene had previously been identified by virtue of its mutation in human colorectal tumors. 1651562 1991
Entrez Id: 4342
Gene Symbol: MOS
MOS 		0.010 GeneticVariation group BEFREE The frequency of the rare 5 kb c-mos allele was significantly higher than that observed in control groups of patients with colorectal neoplasms or lymphoproliferative disorders. 1679639 1991
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.050 AlteredExpression group BEFREE Differential expression of epidermal growth factor-related proteins in human colorectal tumors. 1715580 1991
Entrez Id: 374
Gene Symbol: AREG
AREG 		0.020 Biomarker group BEFREE Immunostaining also detected AR protein in primary and metastatic colorectal tumors but not in normal colon or uninvolved liver. 1715580 1991
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 GeneticVariation group BEFREE Sequence analysis of the p53 gene in colorectal tumors indicated that 64% contained a mutation. 1945416 1991
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.400 AlteredExpression group BEFREE We have analyzed 21 human colorectal tumors and found overexpression of IGF-II in 6 of them (30%). 1975564 1990
Entrez Id: 4953
Gene Symbol: ODC1
ODC1 		0.330 AlteredExpression group BEFREE Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the synthesis of these amines, and activity is elevated in colorectal tumors and polyps. 1976038 1990
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.390 Biomarker group BEFREE Aggressive subtypes of human colorectal tumors frequently exhibit amplification of the c-myc gene. 1992440 1991
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		0.100 AlteredExpression group BEFREE The regulation of carcinoembryonic antigen (CEA) expression by recombinant human interferon-gamma (IFN-gamma) was studied in a series of 7 human colorectal tumor cell lines at various stages of differentiation. 2119252 1990
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.020 Biomarker group BEFREE The regulation of carcinoembryonic antigen (CEA) expression by recombinant human interferon-gamma (IFN-gamma) was studied in a series of 7 human colorectal tumor cell lines at various stages of differentiation. 2119252 1990
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.500 GeneticVariation group BEFREE K-ras gene mutation in colorectal tumors from patients with familial polyposis coli were investigated using oligonucleotide probes specific for a mutation at codon 12, 13, or 61 of the K-ras gene. 2159840 1990
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.390 Biomarker group BEFREE Immunohistochemical demonstration of altered intracellular localization of the C-Myc oncogene product in human colorectal neoplasms. 2193134 1990
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1 		0.020 AlteredExpression group BEFREE Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor. 2224769 1990
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 GeneticVariation group CLINVAR [The effect of occlusion time in the measurement of compliance and resistance of the respiratory system using passive expiration in infants]. 2281069 1990
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.200 AlteredExpression group BEFREE Expression of p21ras in fresh primary and metastatic human colorectal tumors. 3885218 1985
Entrez Id: 4771
Gene Symbol: NF2
NF2 		0.010 Biomarker group BEFREE These results suggest that the NF2 gene is probably involved in some colorectal tumors, but is not the critical chromosome 22q tumor suppressor gene involved in colon tumorigenesis. 7497438 1995
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		0.100 AlteredExpression group BEFREE Mucosa sampled at 5 and 10 cm from the tumor expresses CEA at the same low level as in mucosa of control subjects with no colorectal neoplasm. 7501974 1996
Entrez Id: 7031
Gene Symbol: TFF1
TFF1 		0.020 Biomarker group BEFREE Expression pattern of breast-cancer-associated protein pS2/BCEI in colorectal tumors. 7505265 1994
Entrez Id: 90353
Gene Symbol: CTU1
CTU1 		0.010 Biomarker group BEFREE Expression pattern of breast-cancer-associated protein pS2/BCEI in colorectal tumors. 7505265 1994
Entrez Id: 960
Gene Symbol: CD44
CD44 		0.100 AlteredExpression group BEFREE Alternative splicing of CD44 pre-mRNA in human colorectal tumors. 7513991 1994