Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group BEFREE We investigated expression levels, localization, and proteolytic activity of MMP-7 and local caseinolytic activity in colorectal tumor and paired normal tissues by using real time PCR, casein zymography, immunohistochemistry and in situ casein zymography, respectively. 24930385 2014
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 Biomarker group LHGDN Clinicopathological significance of the gene expression of matrix metalloproteinase-7, insulin-like growth factor-1, insulin-like growth factor-2 and insulin-like growth factor-1 receptor in patients with colorectal cancer: insulin-like growth factor-1 receptor gene expression is a useful predictor of liver metastasis from colorectal cancer. 18636198 2008
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group LHGDN Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis. 19016757 2008
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 Biomarker group LHGDN Matrix metalloproteinases 7 and 9 and their types 1 and 4 tissue inhibitors in tumors and plasma of patients with colorectal cancer. 18214300 2007
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 Biomarker group LHGDN Serum matrix metalloproteinase 7 levels identifies poor prognosis advanced colorectal cancer patients. 17487834 2007
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group LHGDN Matrix metalloproteinase-7 increases resistance to Fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma. 16474169 2006
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 Biomarker group BEFREE Using this approach, we found that HER2 and MMP7 may be down-regulated during distal dissemination of colorectal tumors. 15613710 2005
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group LHGDN Nobiletin, a citrus flavonoid, down-regulates matrix metalloproteinase-7 (matrilysin) expression in HT-29 human colorectal cancer cells. 15725655 2005
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group BEFREE Interestingly, the levels of Tbeta-4 mRNA, beta-catenin, c-Myc, and MMP-7 in metastatic liver lesions were relatively higher, whereas the levels of E-cadherin and Fas were significantly lower than those in the matched primary colorectal tumors. 15235586 2004
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group LHGDN Matrix metalloproteinase-7 expression in colorectal cancer liver metastases: evidence for involvement of MMP-7 activation in human cancer metastases. 11801551 2002
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group BEFREE Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms. 10204802 1999
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group BEFREE These results suggest that matrilysin mRNA expression was correlated with the progression of colorectal tumors, and this enzyme may also play a role in developing metastatic tumors in liver. 8913260 1996
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.100 AlteredExpression group BEFREE These results suggest that matrilysin gene expression by colon adenocarcinoma cells is not sufficient for tumor invasion and metastasis but contributes to the tumorigenicity and progression of colorectal tumors. 8062282 1994