Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 Biomarker group LHGDN Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype. 18983468 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group LHGDN Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes. 17960397 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group LHGDN Impact of the cyclin D1 A870G polymorphism on susceptibility to sporadic colorectal cancer in Taiwan. 16552496 2006
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group LHGDN The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study. 16829689 2006
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group LHGDN Elevated risk of colorectal cancer associated with the AA genotype of the cyclin D1 A870G polymorphism in an Indian population. 16328437 2006
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 AlteredExpression group BEFREE Overexpression of cyclin D1 is observed in one third of colorectal tumors. 15557752 2005
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 Biomarker group LHGDN In conclusion, even in a small number of colorectal tumors, CCND1 gene amplification is a possible mechanism for the increase in cyclin D1 oncoprotein. 15557752 2005
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group BEFREE These data support the hypothesis that the CCND1 A870G polymorphism may increase risk for colorectal neoplasms. 14679024 2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group LHGDN These data support the hypothesis that the CCND1 A870G polymorphism may increase risk for colorectal neoplasms. 14679024 2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group LHGDN Lack of association between CCND1 G870A polymorphism and the risk of breast and colorectal cancers. 14666635 2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 GeneticVariation group LHGDN Association of the cyclin D1 A870G polymorphism with advanced colorectal cancer. 14657069 2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.100 AlteredExpression group BEFREE These findings may be of clinical relevance since human colorectal tumors also frequently display increased expression of both cyclin D1 and Rb. 8649851 1996