×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
Systematic study on genetic and epimutational profile of a cohort of Amsterdam criteria-defined Lynch Syndrome in Singapore.
24710284
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Spectrum of mismatch repair gene mutations and clinical presentation of Hispanic individuals with Lynch syndrome.
28449805
2017
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Molecular screening in Sicilian families with hereditary non-poliposis colorectal cancer (H.N.P.C.C.) syndrome: identification of a novel mutation in MSH2 gene.
25200962
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
RNA-based mutation screening in hereditary nonpolyposis colorectal cancer.
8808596
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions.
22949387
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
9311737
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
HNPCC: six new pathogenic mutations.
15217520
2004
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Malignant fibrous histiocytoma is a rare Lynch syndrome-associated tumor in two German families.
21598002
2011
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
Patient vs. physician as the target of educational outreach about screening for an inherited susceptibility to colorectal cancer.
12537652
2002
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Identification of a one-base germline deletion (codon 888 del C) and an intron splice acceptor site polymorphism in hMSH2.
9222765
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients.
11772966
2002
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
The InSiGHT database: utilizing 100 years of insights into Lynch syndrome.
23443670
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers.
24244552
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Predominant germ-line mutation of the hMSH2 gene in Japanese hereditary non-polyposis colorectal cancer kindreds.
10404063
1999
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
22949379
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients.
8574961
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Germ line mutations of hMSH2 and hMLH1 genes in Japanese families with hereditary nonpolyposis colorectal cancer (HNPCC): usefulness of DNA analysis for screening and diagnosis of HNPCC patients.
8581513
1995
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal?
26485756
2015
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.
8261515
1993
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.
21642682
2011
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
Functional analysis of MSH2 unclassified variants found in suspected Lynch syndrome patients reveals pathogenicity due to attenuated mismatch repair.
24501230
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
18561205
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
GeneticVariation
group
CLINVAR
UMD (Universal mutation database): a generic software to build and analyze locus-specific databases.
10612827
2000
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers.
20591884
2010
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.900
CausalMutation
group
CLINVAR
Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer.
21868491
2012