Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 AlteredExpression disease BEFREE Therefore, we investigated whether salivary levels of MMP-9 and MPO corresponded to plasma levels in patients with coronary artery disease (CAD), both at rest and after acute physical exercise. 30726210 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Association of matrix metalloproteinase-9 C1562T polymorphism and coronary artery disease: a meta-analysis. 24599689 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 AlteredExpression disease BEFREE Circulating levels of MMP2 and MMP9 are independently associated with development of an acute MI rather than stable angina as the initial clinical presentation of coronary artery disease. 18035073 2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Matrix metalloproteinase-9 functional promoter polymorphism 1562C>T increased risk of early-onset coronary artery disease. 21559835 2012
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Lack of association between matrix metalloproteinase-9 and endothelial nitric oxide synthase gene polymorphisms and coronary artery disease in Turkish population. 19435423 2009
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis. 10199873 1999
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Impact of matrix metalloproteinase 9 rs3918242 genetic variant on lipid-lowering efficacy of simvastatin therapy in Chinese patients with coronary heart disease. 28390432 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Association of genetic polymorphisms in matrix metalloproteinase-9 and coronary artery disease in the Chinese Han population: a case-control study. 23819814 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 AlteredExpression disease BEFREE Genetic variation, gene-expression and circulating levels of matrix metalloproteinase-9 in patients with stable coronary artery disease. 21963461 2012
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Haplotypic analysis of the MMP-9 gene in relation to coronary artery disease. 12728308 2003
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE The MMP-9 -1562 C/T polymorphism in the presence of metabolic syndrome increases the risk of clinical events in patients with coronary artery disease. 25191702 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Meta-analysis of MMP9-562C/T and the risk of coronary heart disease. 23328249 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 Biomarker disease BEFREE Of the variety of MMPs, stromelysin-1 and gelatinase B may have key roles in coronary artery atherosclerosis. 12205736 2002
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Association between -1562C>T polymorphism in the promoter region of matrix metalloproteinase-9 and coronary artery disease: a meta-analysis. 24506511 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE The aim of this study was to analyze the occurrence of the -1612 5A/6A, -376C/G, and Glu45Lys polymorphisms of MMP3 and the -1562C/T and R279Q polymorphisms of MMP9 and their relation to the risk of coronary heart disease (CHD; stenosis >/=50% of the diameter in at least one major coronary artery) in a Chinese Han population. 19438845 2009
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Association of matrix metalloproteinases (MMP2, MMP7 and MMP9) genetic variants with left ventricular dysfunction in coronary artery disease patients. 22664146 2012
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 AlteredExpression disease BEFREE The level of MMP-9 was significantly higher in COPD patients with >3 comorbidities, a COTE index of ≥4 and cardiovascular disease as well as coronary heart disease (t=6.40, 2.53, 3.65 and 2.90, P<0.05). 30542429 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Role of serum MMP-9 levels and vitamin D receptor polymorphisms in the susceptibility to coronary artery disease: An association study in Iranian population. 28739397 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 Therapeutic disease RGD Rat coronary atherosclerosis heart disease model can be successfully established by feeding with high-fat diet and intraperitoneal injection of VD3, the permeability of coronary artery in coronary heart disease rat model is significantly increased, which may be related to up-regulation of MMP-9, CD40L, TNF-α and CRP expression. 26261622 2015
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE The co-existence of the IL-18+183 A/G and MMP-9 -1562 C/T polymorphisms is associated with clinical events in coronary artery disease patients. 24040261 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Functional polymorphisms of matrix metallopeptidase-9 and risk of coronary artery disease in a Chinese population. 19283512 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE Association between matrix metalloproteinase 9 C-1562T polymorphism and the risk of coronary artery disease: an update systematic review and meta-analysis. 29507703 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 AlteredExpression disease BEFREE This study provides evidence of an association between expression of MMP-9 and the intravascular presence of C pneumoniae and may suggest a potential pathological mechanism whereby C pneumoniae may contribute to the progression of coronary atherosclerosis. 15772219 2005
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 GeneticVariation disease BEFREE The observation indicates that the polymorphisms in the MMP-9 and PON1 192 genes potentially play a role in the manifestation of coronary atherosclerosis but does not have any effect on the number of diseased vessels in Iran. 20872564 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 Biomarker disease BEFREE Plasma MMP-9 concentration was identified as a novel predictor of CV mortality in patients with coronary artery disease. 12668489 2003