Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE A genetic variant c.553G > T in the apolipoprotein A5 gene is associated with an increased risk of coronary artery disease and altered triglyceride levels in a Chinese population. 16046221 2006
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Apolipoprotein A5 gene polymorphism -1131T-->C: association with plasma lipids and type 2 diabetes mellitus with coronary heart disease in Chinese. 16006256 2005
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Positive Association between APOA5 rs662799 Polymorphism and Coronary Heart Disease: A Case-Control Study and Meta-Analysis. 26309253 2015
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE APOA5 -1131T/C polymorphism and coronary artery disease susceptibility in Chinese population: an updated meta-analysis and review. 26505382 2015
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Interactions between the APOA5 -1131T>C and the FEN1 10154G>T polymorphisms on ω6 polyunsaturated fatty acids in serum phospholipids and coronary artery disease. 20802161 2010
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE However, little is known on the impact of rare APOA5 mutations for the risk of coronary artery disease; therefore, we screened the APOA5 gene in subjects with CAD. 22914599 2012
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE We studied the effects of APOA5 polymorphisms on plasma triglyceride levels in Turks, a population with low levels of HDL cholesterol and a high prevalence of coronary artery disease. 16258166 2006
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE The -1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study. 16682041 2007
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 Biomarker disease BEFREE The independent variants at PCSK9, HMGCR, LPA, APOA5 and LDLR were also associated with increased risk of coronary artery disease in the expected direction. 27516387 2016
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE A single nucleotide polymorphism -1131T>C in the apolipoprotein A5 gene is associated with an increased risk of coronary artery disease and alters triglyceride metabolism in Chinese. 15542401 2004
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 Biomarker disease CTD_human Common variants associated with plasma triglycerides and risk for coronary artery disease. 24097064 2013
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE However, there was no association between APOA5 gene polymorphisms or haplotypes and coronary artery disease as determined by angiography. 15306190 2004
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia. 29263402 2017
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE APOA5 -1131T/C polymorphism is associated with coronary artery disease in a Chinese population: a meta-analysis. 21143013 2011
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE The non-synonymous S19W SNP in APOA5 is also an independent determinant of plasma apo A-I level, severity of coronary atherosclerosis and its progression. 19878569 2009
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Association between DNA variant sites in the apolipoprotein A5 gene and coronary heart disease in Chinese. 15877284 2005
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 Biomarker disease BEFREE Emerging evidences for the opposite role of apolipoprotein C3 and apolipoprotein A5 in lipid metabolism and coronary artery disease. 31836003 2019
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE The possible roles of APOA5 variants in determining the risk of myocardial infarction and coronary artery disease development, as well as in the determination of low-density lipoprotein-particle size or plasma concentrations of C-reactive protein and high-density lipoprotein-cholesterol, are also summarized. 16176166 2005
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE APOA5 -1131T>C and APOC3 -455T>C polymorphisms are associated with an increased risk of coronary heart disease. 26782469 2015
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Apolipoprotein A5 and apolipoprotein C3 single nucleotide polymorphisms are correlated with an increased risk of coronary heart disease: a case-control and meta-analysis study. 26387083 2015
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE However, data for a possible association of APOA5 variants with coronary heart disease are not consistent. 18415697 2008
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Effects of polymorphisms in APOA5 on the plasma levels of triglycerides and risk of coronary heart disease in Jilin, northeast China: a case-control study. 29866721 2018
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE These results shed new light on the role of APOA5 variants in TG metabolism and coronary heart disease risk. 14729863 2004
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 GeneticVariation disease BEFREE Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease. 15177130 2004
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.400 Biomarker disease BEFREE Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study. 16769999 2006