Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.360 | AlteredExpression | disease | BEFREE | These data demonstrate that the PECAM-1 gene is responsive to shear stress in vitro and that decreased PECAM-1 gene expression in 53A carriers may influence reduced progression of vessel stenosis in patients with coronary artery disease. | 12732396 | 2003 | ||||
|
0.360 | Biomarker | disease | CTD_human | Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms. | 28530674 | 2017 | ||||
|
0.360 | Biomarker | disease | BEFREE | PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. | 28512385 | 2017 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | Accordingly, a number of population studies have explored the association of ischaemic heart disease with gene polymorphisms of the inflammatory molecules tumour necrosis factors (TNF) alpha and beta, transforming growth factors (TGF) beta1 and 2, interleukin (IL) 1 and its receptor antagonist (IL 1ra), CD14 (the receptor for lipopolysaccharide), P and E selectins, and platelet endothelial cell adhesion molecule (PECAM) 1. | 11796541 | 2002 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | Genetic analyses of platelet-endothelial cell adhesion molecule-1 (PECAM-1), a key adhesion molecule in the progression of atherosclerosis, have provided conflicting results regarding the role of variation within the PECAM-1 gene and risk for coronary heart disease. | 19183069 | 2009 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | A few studies have investigated an association between coronary heart disease and single nucleotide polymorphisms (SNPs) located in functionally important domains of the PECAM-1/CD31 gene. | 15265022 | 2004 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | Association of Leu125Val polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) gene & soluble level of PECAM-1 with coronary artery disease in Asian Indians. | 15756041 | 2005 |