Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Endothelial nitric oxide synthase and angiotensinogen gene polymorphism in coronary artery diseases in Egypt. 20547537 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Recent genetic studies have shown an association between the -786TC polymorphism in the endothelial nitric oxide synthase gene (NOS3) and coronary artery diseases, but any possible association with hypertension has been controversial. 21194529 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characterized as a risk factor of hypertension and coronary artery disease. 21816783 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE This study, for the first time, suggests an independent association of 894G>T and -786T>C polymorphisms of endothelial nitric oxide synthase gene with coronary artery disease in a Saudi population. 20470943 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 Biomarker disease BEFREE The endothelial nitric oxide synthase gene is associated with coronary artery disease: a meta-analysis. 20861627 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE T-786C polymorphism in the endothelial nitric oxide synthase gene is associated with increased risk of coronary artery disease in a Chinese population. 20215811 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The G894T polymorphism in the eNOS gene might influence coronary atherosclerosis rather than ICAS in Koreans. 21114134 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE G894T polymorphism of eNOS gene was not associated with foot ulcer and diabetic complications, except in the presence of atherosclerotic heart disease. 20642368 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been associated with hypertension and coronary artery disease in several populations worldwide, but results are still controversial. 20083095 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Polymorphisms of the NOS3 gene in Southern Chilean subjects with coronary artery disease and controls. 19931521 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial nitric oxide synthase gene in patients with coronary artery disease. 19434512 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 Biomarker disease BEFREE We conclude that eNOS gene transfection is a valuable approach to augment angiogenic properties of ex vivo expanded EPCs and eNOS-modified EPCs may offer significant advantages than EPCs alone in terms of their clinical use in patients with myocardial ischemia. 19479297 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 Biomarker disease CTD_human Disinhibition of SOD-2 expression to compensate for a genetically determined NO deficit in endothelial cells--brief report. 19696404 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 Biomarker disease BEFREE Patients with coronary artery disease had significantly higher ratios of eNOS T/C and C/C genotypes, which include the C allele, than the T/T genotype. 19761682 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Lack of association between matrix metalloproteinase-9 and endothelial nitric oxide synthase gene polymorphisms and coronary artery disease in Turkish population. 19435423 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Endothelial nitric oxide synthase (eNOS) intron 4a/b polymorphism is associated with coronary artery disease and hypertension in various populations. 19574729 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE -786T>C polymorphism of the endothelial nitric oxide synthase gene in Chilean subjects with coronary artery disease and controls. 17927970 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association of endothelial nitric oxide synthase promoter region (T-786C) gene polymorphism with acute coronary syndrome and coronary heart disease. 18298848 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Endothelial nitric oxide synthase (eNOS) intron 4a/b polymorphism is associated with plasma NO concentrations and coronary artery disease/hypertension in various populations. 18426819 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Smoking-dependent and haplotype-specific effects of endothelial nitric oxide synthase gene polymorphisms on angiographically assessed coronary artery disease in Caucasian- and African-Brazilians. 16842798 2007
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 Biomarker disease CTD_human Role of nitric oxide-producing and -degrading pathways in coronary endothelial dysfunction in chronic kidney disease. 17267746 2007
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The eNOS -786T>C (odds ratio [OR]; 1.61, 95% confidence interval [CI]; 0.97-2.69), 894G>T (OR; 1.12, 95% CI; 0.65-1.92) and 4a4b (OR; 1.44, 95% CI; 0.87-2.39) polymorphisms were not an independent predisposition factor to coronary artery disease. 16842840 2007
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The objective of our study is to evaluate the single locus and combined effects of three different genetic polymorphisms (methylenetetrahydrofolate reductase C677T polymorphism, plasminogen activator inhibitor 4G/5G polymorphism, and endothelial nitric oxide synthase 3-27 base pairs repeat polymorphism) on the presence and extent of coronary artery disease in patients with early-onset coronary artery disease. 16845248 2006
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE In this study, we aimed to investigate the relationship between eNOS gene polymorphism (T-786 C) and coronary artery disease in the Turkish population. 17151815 2006
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Hyperhomocysteinemia, endothelial nitric oxide synthase polymorphism, and risk of coronary artery disease. 16284093 2006