Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 Biomarker disease BEFREE These studies show that miR-21 is an important factor leading to vulnerable plaque instability in ACS, and it can be a predictor of acute adverse events in coronary heart disease. 31764830 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 Biomarker disease BEFREE Droplet digital PCR of serum miR-499, miR-21 and miR-208a for the detection of functionally relevant coronary artery disease. 30126654 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 AlteredExpression disease BEFREE Here, we report that miR-21 is significantly upregulated in mouse atherosclerotic plaques and peripheral monocytes from patients with coronary artery disease. 31704554 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 Biomarker disease BEFREE Effect of miR-21/TLR4/NF-κB pathway on myocardial apoptosis in rats with myocardial ischemia-reperfusion. 30536340 2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 Biomarker disease BEFREE MicroRNA-21 (miR-21) is a short, non-coding RNA that has been implicated in cardiovascular diseases including proliferative vascular disease and ischaemic heart disease. 29659130 2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 Biomarker disease BEFREE Cigarette smoking represses expression of cytokine IL-12 and its regulator miR-21-An observational study in patients with coronary artery disease. 27765464 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 AlteredExpression disease BEFREE Trimetazidine protects against cardiac ischemia/reperfusion injury via effects on cardiac miRNA‑21 expression, Akt and the Bcl‑2/Bax pathway. 27666568 2016
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 AlteredExpression disease BEFREE In addition, miR-21 expression was increased in human tissue samples from patients with ISR compared with coronary artery disease specimen. 26183619 2015
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 Biomarker disease BEFREE MicroRNA-21 negatively regulates Treg cells through a TGF-β1/Smad-independent pathway in patients with coronary heart disease. 26383248 2015
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.100 Biomarker disease BEFREE MiR-21 antagonism therefore emerges as an interesting strategy to improve dysfunctional APCs in patients with coronary artery disease. 20489163 2010