Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
0.360 Biomarker disease CTD_human Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms. 28530674 2017
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
0.360 Biomarker disease BEFREE PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. 28512385 2017
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
0.360 GeneticVariation disease BEFREE Genetic analyses of platelet-endothelial cell adhesion molecule-1 (PECAM-1), a key adhesion molecule in the progression of atherosclerosis, have provided conflicting results regarding the role of variation within the PECAM-1 gene and risk for coronary heart disease. 19183069 2009
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
0.360 GeneticVariation disease BEFREE Association of Leu125Val polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) gene & soluble level of PECAM-1 with coronary artery disease in Asian Indians. 15756041 2005
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
0.360 GeneticVariation disease BEFREE A few studies have investigated an association between coronary heart disease and single nucleotide polymorphisms (SNPs) located in functionally important domains of the PECAM-1/CD31 gene. 15265022 2004
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
0.360 AlteredExpression disease BEFREE These data demonstrate that the PECAM-1 gene is responsive to shear stress in vitro and that decreased PECAM-1 gene expression in 53A carriers may influence reduced progression of vessel stenosis in patients with coronary artery disease. 12732396 2003
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
0.360 GeneticVariation disease BEFREE Accordingly, a number of population studies have explored the association of ischaemic heart disease with gene polymorphisms of the inflammatory molecules tumour necrosis factors (TNF) alpha and beta, transforming growth factors (TGF) beta1 and 2, interleukin (IL) 1 and its receptor antagonist (IL 1ra), CD14 (the receptor for lipopolysaccharide), P and E selectins, and platelet endothelial cell adhesion molecule (PECAM) 1. 11796541 2002