Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 25886
Gene Symbol: POC1A
POC1A
0.020 GeneticVariation disease BEFREE (Optical Coherence Tomography in Patients With Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease [SOFT-MI]; NCT02783963). 30343070 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 GeneticVariation disease BEFREE -308G>A and -1031T>C tumor necrosis factor gene polymorphisms in Tunisian patients with coronary artery disease. 19803813 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.100 GeneticVariation disease BEFREE -786T>C polymorphism of the endothelial nitric oxide synthase gene in Chilean subjects with coronary artery disease and controls. 17927970 2008
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
0.100 GeneticVariation disease BEFREE -94 ATTG insertion/deletion polymorphism of the NFKB1 gene is associated with coronary artery disease in Han and Uygur women in China. 24818816 2014
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.080 GeneticVariation disease BEFREE 1.The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer. 19650794 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 GeneticVariation disease BEFREE 10-Year Associations Between Tumor Necrosis Factor Receptors 1 and 2 and Cardiovascular Events in Patients With Stable Coronary Heart Disease: A CLARICOR (Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease) Trial Substudy. 29686027 2018
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
0.500 GeneticVariation disease BEFREE 14 association studies focusing on three polymorphisms (A379V, V279F and R92H) in PLA2G7 gene and risk of CHD were included in meta-analysis, covering a total of 8,280 cases and 5,656 controls. 20926117 2010
Entrez Id: 1118
Gene Symbol: CHIT1
CHIT1
0.010 GeneticVariation disease BEFREE 24 bp duplication of CHIT1 gene is not correlated with coronary artery disease in Corsica Island (France). 17916351 2007
Entrez Id: 760
Gene Symbol: CA2
CA2
0.040 Biomarker disease BEFREE 256 patients without a prior history of coronary artery disease had undergone a chest CT. CT images were reviewed to detect CAC. 30696608 2019
Entrez Id: 788
Gene Symbol: SLC25A20
SLC25A20
0.040 Biomarker disease BEFREE 256 patients without a prior history of coronary artery disease had undergone a chest CT. CT images were reviewed to detect CAC. 30696608 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 GeneticVariation disease BEFREE 3 years) with chronic stable angina due to angiographically documented coronary artery disease, all of whom had failed conventional therapy (drugs, PTCA, and/or CABG), were treated with direct myocardial injection of phVEGF(165) via a minithoracotomy. 10961959 2000
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 AlteredExpression disease BEFREE 3-hydroxy-3-methylglutaryl (HMG)-coenzyme A (CoA) reductase inhibitors, or statins, significantly reduce cardiovascular events and mortality in patients with or without coronary artery disease and reduce plasma CRP levels in humans. 15790934 2005
Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
0.050 Biomarker disease BEFREE 40 ACS subjects who had had a definite diagnosis of CHD for more than 2 years with no history of T2DM were recuited as the CACS group(chronic CHD with ACS group). 30670045 2019
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
0.050 Biomarker disease BEFREE 40 ACS subjects who had had a definite diagnosis of CHD for more than 2 years with no history of T2DM were recuited as the CACS group(chronic CHD with ACS group). 30670045 2019
Entrez Id: 23659
Gene Symbol: PLA2G15
PLA2G15
0.050 Biomarker disease BEFREE 40 ACS subjects who had had a definite diagnosis of CHD for more than 2 years with no history of T2DM were recuited as the CACS group(chronic CHD with ACS group). 30670045 2019
Entrez Id: 338
Gene Symbol: APOB
APOB
0.500 GeneticVariation disease BEFREE 5' ins/del and 3' VNTR polymorphisms in the apolipoprotein B gene in relation to lipids and coronary artery disease. 18254714 2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 Biomarker disease BEFREE 9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells. 26487755 2015
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.020 Biomarker disease BEFREE 9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells. 26487755 2015
Entrez Id: 5972
Gene Symbol: REN
REN
0.100 Biomarker disease BEFREE : The renin-angiotensin system plays an important role in the regulation of blood pressure and the development of coronary artery disease. 29474203 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.100 Biomarker disease BEFREE Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms. 10500308 1999
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.400 GeneticVariation disease BEFREE Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms. 10500308 1999
Entrez Id: 348
Gene Symbol: APOE
APOE
0.700 GeneticVariation disease BEFREE Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. 16682673 2006
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.100 Biomarker disease BEFREE Coronary artery disease and depression: possible role of brain-derived neurotrophic factor and serotonin transporter gene polymorphisms. 19885623 2009
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.040 Biomarker disease BEFREE CHD in Chinese population is strongly associated with HLA-DRB1*01 and DRB1*04 haplotypes, and formation of CD4(+)CD28(null) T cells was related to HLA-DRB1*01, DRB1*04, and DRB1*15 alleles. 20842443 2011
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.020 Biomarker disease BEFREE CHD in Chinese population is strongly associated with HLA-DRB1*01 and DRB1*04 haplotypes, and formation of CD4(+)CD28(null) T cells was related to HLA-DRB1*01, DRB1*04, and DRB1*15 alleles. 20842443 2011